Ultrastructural Aspects of Female Aging Wistar Rat Epithelium Tongue: A HRSEM and TEM Study

Background: There is general consensus that the effects of intrinsic aging on the oral mucosa are relatively small, though potentially important to understanding the pathologies present in the aged animals. Objective: In this paper, the development of dorsal surface of rat tongue was examined using...

Full description

Saved in:
Bibliographic Details
Published in:Gerontology (Basel) 2009-01, Vol.55 (4), p.442-448
Main Authors: Lopes, Marilia Gabriela de Oliveira, Watanabe, Ii-sei, Soares, Luís Eduardo Silva, da Silva, Newton Soares, da Silva, Marcelo Cavenaghi Pereira
Format: Article
Language:English
Subjects:
Aging
Aging - pathology
Animals
Biological and medical sciences
Cytoskeleton - ultrastructure
Development. Metamorphosis. Moult. Ageing
Epithelium - ultrastructure
Experimental Section
Female
Females
Fundamental and applied biological sciences. Psychology
Gerontology
Microscopy
Microscopy, Electron, Scanning
Microscopy, Electron, Transmission
Mitochondria - ultrastructure
Mouth Mucosa - ultrastructure
Rats
Rats, Wistar
Rodents
Tongue
Tongue - ultrastructure
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: There is general consensus that the effects of intrinsic aging on the oral mucosa are relatively small, though potentially important to understanding the pathologies present in the aged animals. Objective: In this paper, the development of dorsal surface of rat tongue was examined using transmission electron microscopy (TEM) and high-resolution scanning electron microscopy (HRSEM) in order to understand the age-related structural and ultrastructural changes experimentally. Methods: In this study, we used female rats 75 and 720 days old (adult and aging). Tissues of rat tongue were prepared and the specimens submitted to HRSEM and TEM techniques. Results: The analysis of HRSEM and TEM demonstrated that the same characteristic keratinous epithelium was found in aging animals, however with some modifications. Conclusion: We agree that there are obvious changes in the oral mucosa with aging and these modifications can be observed starting from the ultrastructural aspects.
ISSN:0304-324X
1423-0003
DOI:10.1159/000216829