Gallbladder wall thickening: MR imaging and pathologic correlation with emphasis on layered pattern

The aim of this study was to correlate MR findings of gallbladder wall thickening with pathologic findings on the basis of the layered pattern and to evaluate the diagnostic value of MR imaging in gallbladder disease. We retrospectively evaluated the source images of HASTE sequences for MR cholangio...

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Bibliographic Details
Published in:European radiology 2005-04, Vol.15 (4), p.694-701
Main Authors: Jung, S E, Lee, J M, Lee, K, Rha, S E, Choi, B G, Kim, E K, Hahn, S T
Format: Article
Language:English
Subjects:
Adult
Aged
Cholecystitis
Correlation
Female
Gallbladder
Gallbladder - pathology
Gallbladder cancer
Gallbladder diseases
Histopathology
Humans
Magnetic Resonance Imaging
Male
Medical imaging
Middle Aged
Retrospective Studies
Thickening
Thin films
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Summary:The aim of this study was to correlate MR findings of gallbladder wall thickening with pathologic findings on the basis of the layered pattern and to evaluate the diagnostic value of MR imaging in gallbladder disease. We retrospectively evaluated the source images of HASTE sequences for MR cholangiography in 144 patients with gallbladder wall thickening. The layered pattern of thickened wall was classified into four patterns. Type 1 shows two layers with a thin hypointense inner layer and thick hyperintense outer layer. Type 2 has two layers of ill-defined margin. Type 3 shows multiple hyperintense cystic spaces in the wall. Type 4 shows diffuse nodular thickening without layering. MR findings of a layered pattern of thickened gallbladder were well correlated with histopathology. Chronic cholecystitis matched to type 1, acute cholecystitis corresponded to type 2, adenomyomatosis showed type 3, and the gallbladder carcinomas showed type 4. All four layered patterns were associated with PPV of 73% or greater, sensitivity of 92% or greater and specificity of 95% or greater. Our results indicate that MR findings of gallbladder wall thickening are characteristic in each entity and correlate well with pathologic findings. The classification of the layered pattern may be valuable for interpreting thickened gallbladder wall.
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-004-2539-2