Isolation of Bordetella pertussis in blood culture from a patient with multiple myeloma

Bordetella pertussis is a fastidious aerobic, Gram-negative coccobacillus that causes the classical disease of whooping cough. We present a 63 years old man with multiple myeloma who was admitted to the medical department with cough, hoarseness and fever. Bronchopneumonia was suspected and two cours...

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Bibliographic Details
Published in:The Journal of infection 2006, Vol.52 (1), p.e11-e13
Main Authors: Trøseid, Marius, Jonassen, Tom Øystein, Steinbakk, Martin
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Bacteraemia
Bacteremia - etiology
Bacteremia - microbiology
Blood culture
Bordetella pertussis
Bordetella pertussis - isolation & purification
Humans
Immunocompromized
Male
Middle Aged
Multiple myeloma
Multiple Myeloma - complications
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Summary:Bordetella pertussis is a fastidious aerobic, Gram-negative coccobacillus that causes the classical disease of whooping cough. We present a 63 years old man with multiple myeloma who was admitted to the medical department with cough, hoarseness and fever. Bronchopneumonia was suspected and two courses of beta-lactam antibiotics had beneficial effect on his clinical condition, but his respiratory symptoms persisted. Eventually, B. pertussis grew in an aerobic blood culture. Delayed treatment with clarithromycin had little or no effect on his cough. To our knowledge this is the third reported case of B. pertussis bacteraemia. All three patients have been immunocompromized. Growth in blood culture may be slow, and prolonged incubation (at least 6 days) of the blood culture bottles and subculture to a special culture medium is necessary for isolation of B. pertussis.
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2005.04.014