Autologous Transplant of Submandibular Gland as a Source of Tears: Demonstration of Function on Tc-99m Pertechnetate Scintigraphy

Severe damage to the cornea occurs if it dries. Autologous transplant of the submandibular salivary gland to supply conjunctival moisture is a therapeutic option, although saliva itself may be incompatible with a long-term healthy cornea. A 65-year-old man with previous denervation of his left lacri...

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Bibliographic Details
Published in:Clinical nuclear medicine 2006-01, Vol.31 (1), p.46-47
Main Authors: Chatterton, Barry E, Crompton, John L
Format: Article
Language:English
Subjects:
Aged
Dry Eye Syndromes - diagnostic imaging
Dry Eye Syndromes - surgery
Graft Rejection - diagnostic imaging
Graft Rejection - etiology
Humans
Keratitis - diagnostic imaging
Keratitis - etiology
Male
Radionuclide Imaging
Radiopharmaceuticals
Sodium Pertechnetate Tc 99m
Submandibular Gland - diagnostic imaging
Submandibular Gland - transplantation
Tears - diagnostic imaging
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Summary:Severe damage to the cornea occurs if it dries. Autologous transplant of the submandibular salivary gland to supply conjunctival moisture is a therapeutic option, although saliva itself may be incompatible with a long-term healthy cornea. A 65-year-old man with previous denervation of his left lacrimal gland resulting from neurosurgical complications presented with chronic keratitis 13 years after an autologous vascularized transplant of his right submandibular gland into the temporal fossa. Its secretory duct was implanted into the conjunctival fornix. The scan was performed to determine the location and extent of functioning graft tissue before possible removal.
ISSN:0363-9762
1536-0229
DOI:10.1097/01.rlu.0000191885.19957.e8