A millisecond micromixer via single-bubble-based acoustic streaming

We present ultra-fast homogeneous mixing inside a microfluidic channel via single-bubble-based acoustic streaming. The device operates by trapping an air bubble within a "horse-shoe" structure located between two laminar flows inside a microchannel. Acoustic waves excite the trapped air bu...

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Bibliographic Details
Published in:Lab on a chip 2009-01, Vol.9 (18), p.2738-2741
Main Authors: Ahmed, Daniel, Mao, Xiaole, Shi, Jinjie, Juluri, Bala Krishna, Huang, Tony Jun
Format: Article
Language:English
Subjects:
Acoustic Stimulation
Algorithms
Dimethylpolysiloxanes - chemistry
Equipment Design
Microfluidics - instrumentation
Particle Size
Surface Tension
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Summary:We present ultra-fast homogeneous mixing inside a microfluidic channel via single-bubble-based acoustic streaming. The device operates by trapping an air bubble within a "horse-shoe" structure located between two laminar flows inside a microchannel. Acoustic waves excite the trapped air bubble at its resonance frequency, resulting in acoustic streaming, which disrupts the laminar flows and triggers the two fluids to mix. Due to this technique's simple design, excellent mixing performance, and fast mixing speed (a few milliseconds), our single-bubble-based acoustic micromixer may prove useful for many biochemical studies and applications.
ISSN:1473-0197
1473-0189
DOI:10.1039/b903687c