Suspected vasculitis in an adolescent female with cardiomyopathy, myocardial infarction, and heart failure requiring heart transplantation

A 15-year-old girl presented with dilated cardiomyopathy, positive cardiac markers, and electrocardiogram changes suggestive of acute coronary syndrome. Coronary angiography showed giant dilated coronary arteries. Pathological evidence for cardiomyopathy with acute myocardial infarction was present...

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Bibliographic Details
Published in:Journal of adolescent health 2006, Vol.38 (1), p.60-64
Main Authors: Nabatian, Sepideh, Quinn, Patrick, DuBrow, Ira, Rosenberg, Michael J., Lakier, Jeffrey
Format: Article
Language:English
Subjects:
Acute coronary syndrome
Adolescent
Cardiac failure
Cardiomyopathy, Dilated
Coronary Aneurysm - etiology
Coronary Angiography
Female
Heart Transplantation
Humans
Myocardial Infarction - etiology
Vasculitis - complications
Vasculitis - diagnosis
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Summary:A 15-year-old girl presented with dilated cardiomyopathy, positive cardiac markers, and electrocardiogram changes suggestive of acute coronary syndrome. Coronary angiography showed giant dilated coronary arteries. Pathological evidence for cardiomyopathy with acute myocardial infarction was present in the explanted heart. Further investigation suggested evidence for a systemic vasculitis: polyangiitis overlap syndrome.
ISSN:1054-139X
1879-1972
DOI:10.1016/j.jadohealth.2005.01.003