Secondary Pulmonary Syphilis: Report of A Likely Case and Literature Review

We report the case of a homosexual, HIV-positive man with typical secondary syphilis and multiple excavated pulmonary subpleural nodules. Syphilis with direct pulmonary involvement was suggested by a positive result of PCR of a bronchoalveolar lavage fluid specimen, then confirmed by a positive ther...

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Bibliographic Details
Published in:Clinical infectious diseases 2006-02, Vol.42 (3), p.e11-e15
Main Authors: David, Gary, Perpoint, Thomas, Boibieux, André, Pialat, Jean-Baptiste, Salord, Hélène, Devouassoux, Modjgan, Chidiac, Christian, Peyramond, Dominique
Format: Article
Language:English
Subjects:
Adult
Anti-Bacterial Agents - therapeutic use
HIV Infections - complications
Humans
Male
Penicillin G - therapeutic use
Pneumonia, Bacterial - diagnosis
Pneumonia, Bacterial - drug therapy
Pneumonia, Bacterial - microbiology
Pneumonia, Bacterial - pathology
Syphilis - diagnosis
Syphilis - drug therapy
Syphilis - etiology
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Summary:We report the case of a homosexual, HIV-positive man with typical secondary syphilis and multiple excavated pulmonary subpleural nodules. Syphilis with direct pulmonary involvement was suggested by a positive result of PCR of a bronchoalveolar lavage fluid specimen, then confirmed by a positive therapeutic test result. Only 9 reports of pulmonary involvement in secondary syphilis have been reported to date in the English-language literature. Clinicians should be aware of this atypical localization of syphilis.
ISSN:1058-4838
1537-6591
DOI:10.1086/499104