Haemophilia imaging: a review

Haemophilia disorders are characterised by a blood coagulation anomaly leading to prolonged and excessive bleeding. Imaging provides an essential role in the investigation of both the musculoskeletal and the non-musculoskeletal complications of haemophilia. Our institution is home to a large tertiar...

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Bibliographic Details
Published in:Skeletal radiology 2009-10, Vol.38 (10), p.949-957
Main Authors: Maclachlan, Jody, Gough-Palmer, Antony, Hargunani, Rikin, Farrant, Joanna, Holloway, Brian
Format: Article
Language:English
Subjects:
Biological and medical sciences
Bone Diseases - diagnosis
Bone Diseases - etiology
Diagnostic Imaging - methods
Hematologic and hematopoietic diseases
Hemophilia A - complications
Hemophilia A - diagnosis
Humans
Imaging
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Medicine
Medicine & Public Health
Muscular Diseases - diagnosis
Muscular Diseases - etiology
Nuclear Medicine
Orthopedics
Osteoarticular system. Muscles
Pathology
Platelet diseases and coagulopathies
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radiology
Review Article
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Summary:Haemophilia disorders are characterised by a blood coagulation anomaly leading to prolonged and excessive bleeding. Imaging provides an essential role in the investigation of both the musculoskeletal and the non-musculoskeletal complications of haemophilia. Our institution is home to a large tertiary referral centre for haemophilia treatment. Using our broad experience, we present a multi-modality pictorial review of the musculoskeletal manifestations of haemophilia, including haemophilic arthropathy, intra-muscular haemorrhage and haemophilic pseudotumour. The main imaging features of haemophilic arthropathy are described, including synovial hypertrophy, haemosiderin deposition, sub-chondral cyst formation and loss of joint space.
ISSN:0364-2348
1432-2161
DOI:10.1007/s00256-008-0586-5