Magnetic Resonance Imaging for Prenatal Diagnosis of Multisystem Disease: Megacystis Microcolon Intestinal Hypoperistalsis Syndrome

We discuss a third-trimester diagnosis of Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) using magnetic resonance imaging (MRI) and consider the benefits of MRI as a noninvasive imaging technique after routine ultrasonography reveals genitourinary pathology requiring further eluci...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2009-09, Vol.74 (3), p.592-594
Main Authors: Munch, Erika M.S, Cisek, Lawrence J, Roth, David R
Format: Article
Language:English
Subjects:
Abnormalities, Multiple - diagnosis
Adult
Colon - abnormalities
Esophagus - abnormalities
Fatal Outcome
Female
Humans
Infant, Newborn
Intestinal Obstruction - diagnosis
Magnetic Resonance Imaging
Pregnancy
Prenatal Diagnosis - methods
Syndrome
Urinary Bladder - abnormalities
Urology
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Summary:We discuss a third-trimester diagnosis of Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) using magnetic resonance imaging (MRI) and consider the benefits of MRI as a noninvasive imaging technique after routine ultrasonography reveals genitourinary pathology requiring further elucidation. MMIHS is a rare cause of functional gastrointestinal and genitourinary obstruction in newborns. Because of the poor prognosis of MMIHS, prenatal diagnosis is warranted for optimal prenatal counseling and postnatal treatment. Although MMIHS commonly presents on ultrasonography, the limitations of ultrasonography make definitive diagnosis difficult. However, MRI is safe, accurate, and can be used for early prenatal diagnoses of multisystem diseases.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2009.02.071