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Epithelial Lacrimal Gland Tumors: A Clinicopathological Study of 18 Cases

The aim of this study was to report the clinicopathological features of 18 epithelial tumors of the lacrimal gland treated in a single institution. Clinical data and treatment were recorded and histological features reviewed. Twelve tumors (66.7%) were adenoid cystic carcinoma (ACC), 5 (27.8%) pleom...

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Bibliographic Details
Published in:Otolaryngology-head and neck surgery 2006-02, Vol.134 (2), p.321-325
Main Authors: Perez, Danyel E.C., Pires, Fábio R., Almeida, Oslei P., Kowalski, Luiz P.
Format: Article
Language:English
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Summary:The aim of this study was to report the clinicopathological features of 18 epithelial tumors of the lacrimal gland treated in a single institution. Clinical data and treatment were recorded and histological features reviewed. Twelve tumors (66.7%) were adenoid cystic carcinoma (ACC), 5 (27.8%) pleomorphic adenoma (PA), and 1 (5.5%) carcinoma ex pleomorphic adenoma. All patients with ACC presented with advanced clinical stage, and most were treated by wide surgical resection followed by adjuvant radiotherapy. No recurrence was observed in 4 cases of ACC; however, 7 patients died from persistence of disease or by local and/or distant recurrence. All PA patients were successfully treated by surgical resection. Epithelial lacrimal gland tumors are mainly PA and ACC, and malignancies are more common than benign tumors. Although ACC presented typically with advanced clinical stage, 33% of the patients survived without tumor recurrence or metastasis. EBM rating: C-4
ISSN:0194-5998
1097-6817
DOI:10.1016/j.otohns.2005.09.024