Structural-functional model of the mitotic chromosome

In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of d...

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Bibliographic Details
Published in:Biochemistry (Moscow) 2006-01, Vol.71 (1), p.1-9
Main Authors: Polyakov, V Yu, Zatsepina, O V, Kireev, I I, Prusov, A N, Fais, D I, Sheval, E V, Koblyakova, Yu V, Golyshev, S A, Chentsov, Yu S
Format: Article
Language:English
Subjects:
Animals
Calcium - metabolism
Chromatin - chemistry
Chromatin - ultrastructure
Chromosomal Proteins, Non-Histone - chemistry
Chromosomal Proteins, Non-Histone - metabolism
Chromosomes - chemistry
Chromosomes - metabolism
Chromosomes - ultrastructure
Chromosomes, Human - chemistry
Chromosomes, Human - metabolism
Chromosomes, Human - ultrastructure
DNA - chemistry
Euchromatin - chemistry
Euchromatin - metabolism
Heterochromatin - chemistry
Heterochromatin - metabolism
Histones - chemistry
Histones - metabolism
Humans
Interphase
Mitosis
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Summary:In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of discreteness of structural levels of DNA compactization.
ISSN:0006-2979
1608-3040
0320-9725
DOI:10.1134/S0006297906010019