Retroperitoneoscopic Versus Open Surgical Radical Nephrectomy for Large Renal Cell Carcinoma in Clinical Stage cT2 or cT3a: Quality of Life, Pain and Reconvalescence

• Published in: European urology 2006-02, Vol.49 (2), p.314-323
• Main Authors: Dillenburg, Wolfgang, Poulakis, Vassilis, Skriapas, Konstantinos, de Vries, Rachelle, Ferakis, Nikolaos, Witzsch, Ulrich, Melekos, Michael, Becht, Edward
• Format: Article
• Language: English
• Subjects: Aged; Analysis of Variance; Biological and medical sciences; Body Mass Index; Carcinoma, Renal Cell - pathology; Carcinoma, Renal Cell - surgery; Convalescence; Disease-Free Survival; Extraperitoneal; Female; Follow-Up Studies; Humans; Kidney cancer; Kidney Neoplasms - pathology; Kidney Neoplasms - surgery; Kidneys; Laparoscopy; Large renal tumor; Male; Medical sciences; Middle Aged; Neoplasm Recurrence, Local - prevention & control; Neoplasm Staging; Nephrectomy; Nephrectomy - methods; Nephrology. Urinary tract diseases; Pain Measurement; Pain, Postoperative - etiology; Prospective Studies; Quality of Life; Renal cell carcinoma; Retroperitoneoscopy; Time Factors; Treatment Outcome; Tumors of the urinary system
• ISSN: 0302-2838; 1873-7560
• DOI: 10.1016/j.eururo.2005.10.021

To determine whether retroperitoneoscopic radical nephrectomy for large renal cell carcinoma in stage cT2 or cT3a is a feasible, safe and effective therapy option and if it shows any advantage regarding quality of life in comparison to open procedure. 23 patients who underwent RPNx for tumor size greater than 7cm (group 1) were matched and compared with 25 patients, who underwent ONx (group 2) for tumor with similar size characteristics. Patient and surgical data, QoL variables and complications were statistically analyzed. The median followup was 12 (range: 6–18) months for both groups. Group 1 had significantly (p