Structure and Mechanism of DNA Polymerase β

Beard and Wilson review the structure and mechanism of pol beta, the key polymerase that fills in replacing single-nucleotide gaps in DNA.

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Bibliographic Details
Published in:Chemical reviews 2006-02, Vol.106 (2), p.361-382
Main Authors: Beard, William A, Wilson, Samuel H
Format: Article
Language:English
Subjects:
Animals
Binding Sites
Catalysis
Crystallography, X-Ray
Deoxyribonucleic acid
DNA
DNA - chemical synthesis
DNA - genetics
DNA - metabolism
DNA damage
DNA Polymerase beta - chemistry
DNA Polymerase beta - genetics
DNA Polymerase beta - metabolism
DNA Repair
Genetics
Humans
Kinetics
Magnetic Resonance Spectroscopy
Metals - metabolism
Protein Conformation
Structure-Activity Relationship
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Description
Summary:Beard and Wilson review the structure and mechanism of pol beta, the key polymerase that fills in replacing single-nucleotide gaps in DNA.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr0404904