Transcriptome analyses revealed diverse expression changes in ago1 and hyl1 Arabidopsis mutants

MicroRNAs (miRNAs) are 20-24 nucleotide endogenous regulatory molecules conserved in higher eukaryotes. In Arabidopsis, miRNAs are produced through step-wise cleavages of primary miRNA precursors (pri-miRNAs) by DICER-LIKE1 (DCL1). This cleavage step is also supported by a double-stranded RNA-bindin...

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Published in:Plant and cell physiology 2009-09, Vol.50 (9), p.1715-1720
Main Authors: Kurihara, Y.(RIKEN, Yokohama (Japan). Plant Science Center), Kaminuma, E, Matsui, A, Kawashima, M, Tanaka, M, Morosawa, T, Ishida, J, Mochizuki, Y, Shinozaki, K, Toyoda, T, Seki, M
Format: Article
Language:English
Subjects:
AGO1
Arabidopsis
Arabidopsis - genetics
Arabidopsis - metabolism
Arabidopsis Proteins - genetics
Arabidopsis Proteins - metabolism
ARABIDOPSIS THALIANA
Argonaute Proteins
ARN
Gene Expression Profiling
Gene Expression Regulation, Plant
Genome, Plant
HYL1
MicroRNA
MicroRNAs - metabolism
MUTANT
MUTANTES
MUTANTS
Mutation
Oligonucleotide Array Sequence Analysis
RNA
RNA, Plant - metabolism
RNA-Binding Proteins - genetics
RNA-Binding Proteins - metabolism
Tiling array
TRANSCRIPCION
TRANSCRIPTION
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Summary:MicroRNAs (miRNAs) are 20-24 nucleotide endogenous regulatory molecules conserved in higher eukaryotes. In Arabidopsis, miRNAs are produced through step-wise cleavages of primary miRNA precursors (pri-miRNAs) by DICER-LIKE1 (DCL1). This cleavage step is also supported by a double-stranded RNA-binding protein, HYPONASTIC LEAVES1 (HYL1). In many cases, mature miRNA is predominantly incorporated into an endonuclease, ARGONAUTE1 (AGO1), which degrades miRNA-targeted mRNAs. Here, we examined and revealed whole genome transcriptomes in ago1-25 and hyl1-2 mutants using tiling arrays. The data in this paper are valuable for understanding the relationship between the miRNA pathway and its effect on transcriptomes.
ISSN:0032-0781
1471-9053
DOI:10.1093/pcp/pcp109