Effect of Transvenous Electrical Cardioversion on Plasma Cardiac Troponin I Concentrations in Horses with Atrial Fibrillation

Background: Whether electrical cardioversion of cardiac arrhythmias results in cardiomyocyte damage is unknown. Objective: To describe effect of transvenous electrical cardioversion (TVEC) on plasma cardiac troponin I (cTnI) concentration in horses. Animals: All horses presented to the Cornell Unive...

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Bibliographic Details
Published in:Journal of veterinary internal medicine 2009-09, Vol.23 (5), p.1103-1107
Main Authors: Jesty, S.A., Kraus, M., Gelzer, A., Rishniw, M., Moïse, N.S.
Format: Article
Language:English
Subjects:
Animals
Arrhythmia
Atrial Fibrillation - blood
Atrial Fibrillation - therapy
Atrial Fibrillation - veterinary
Biomarker
Electric Countershock - adverse effects
Electric Countershock - methods
Electric Countershock - veterinary
Equine
Female
Heart
Horse Diseases - blood
Horse Diseases - therapy
Horses
Male
Prospective Studies
Statistics, Nonparametric
Troponin I - blood
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Summary:Background: Whether electrical cardioversion of cardiac arrhythmias results in cardiomyocyte damage is unknown. Objective: To describe effect of transvenous electrical cardioversion (TVEC) on plasma cardiac troponin I (cTnI) concentration in horses. Animals: All horses presented to the Cornell University Hospital for Animals for cardioversion of atrial fibrillation between May 2006 and October 2008 were eligible for inclusion in the study. Owners of 14 horses elected for TVEC and each horse was then enrolled (16 procedures). Methods: Prospective observational study measuring concentrations of plasma cTnI before and after TVEC. Results: Median cTnI concentration increased from 0.045 ng/mL at baseline (range 0.0–0.20 ng/mL) to 0.11 ng/mL after TVEC (range 0.0–3.73 ng/mL) (P= .036). This increase was not associated with the number of shocks delivered, maximal energy delivered, cumulative energy delivered, chronicity of atrial fibrillation before cardioversion, or positioning of the pulmonary artery catheter. Conclusions: The increase in cTnI is unlikely to be clinically important. The increase might be correlated with persistent atrial dysfunction after TVEC, suggesting that a longer convalescent period after the procedure could be warranted.
ISSN:0891-6640
1939-1676
DOI:10.1111/j.1939-1676.2009.0369.x