Vitamin D deficiency and insufficiency in pregnant women: a longitudinal study

Maternal vitamin D insufficiency is associated with childhood rickets and longer-term problems including schizophrenia and type 1 diabetes. Whilst maternal vitamin D insufficiency is common in mothers with highly pigmented skin, little is known about vitamin D status of Caucasian pregnant women. The...

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Bibliographic Details
Published in:British journal of nutrition 2009-09, Vol.102 (6), p.876-881
Main Authors: Holmes, Valerie A., Barnes, Maria S., Alexander, H. Denis, McFaul, Peter, Wallace, Julie M. W.
Format: Article
Language:English
Subjects:
25-hydroxycholecalciferol
Adult
Biological and medical sciences
blood plasma
Blood tests
Dietary Supplements - utilization
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Gestational Age
high latitude northern countries
Human and Clinical Nutrition
Humans
Longitudinal Studies
maternal nutrition
Maternal Nutritional Physiological Phenomena
Mental disorders
multivitamin supplements
nutritional status
Parity
Pregnancy
Pregnancy Complications - blood
Pregnancy Complications - drug therapy
pregnant women
Prenatal care
Seasons
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vitamin D
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D - therapeutic use
Vitamin D Deficiency - blood
Vitamin D Deficiency - drug therapy
Vitamin D insufficiency
Vitamin D supplementation
vitamin deficiencies
White people
Whites
Young Adult
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Summary:Maternal vitamin D insufficiency is associated with childhood rickets and longer-term problems including schizophrenia and type 1 diabetes. Whilst maternal vitamin D insufficiency is common in mothers with highly pigmented skin, little is known about vitamin D status of Caucasian pregnant women. The aim was to investigate vitamin D status in healthy Caucasian pregnant women and a group of age-matched non-pregnant controls living at 54–55°N. In a longitudinal study, plasma 25-hydroxyvitamin D (25(OH)D) was assessed in ninety-nine pregnant women at 12, 20 and 35 weeks of gestation, and in thirty-eight non-pregnant women sampled concurrently. Plasma 25(OH)D concentrations were lower in pregnant women compared to non-pregnant women (P 
ISSN:0007-1145
1475-2662
DOI:10.1017/S0007114509297236