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Association of Common Carotid Intimal Medial Thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus

To determine the association of Common Carotid Intimal Medial Thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus. This is an observational study carried out in 200 type 2 diabetic patients. Age, gender, duration of diabetes, history of ischaemic heart...

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Published in:	Journal of the Pakistan Medical Association 2009-09, Vol.59 (9), p.590-593
Main Authors:	MUJEEB-UR-REHMAN ABID BUTT, ZAKARIA, Manzar
Format:	Article
Language:	English
Subjects:	Adult Aged Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Body Mass Index Cardiology. Vascular system Carotid Artery, Common - pathology Cholesterol, HDL Coronary Artery Disease - epidemiology Diabetes. Impaired glucose tolerance Diabetic Angiopathies - epidemiology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female General aspects Humans Male Medical sciences Middle Aged Risk Factors Tunica Intima - pathology Tunica Media - pathology
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creator	MUJEEB-UR-REHMAN ABID BUTT ZAKARIA, Manzar
description	To determine the association of Common Carotid Intimal Medial Thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus. This is an observational study carried out in 200 type 2 diabetic patients. Age, gender, duration of diabetes, history of ischaemic heart disease, hypertension and smoking was recorded. Body mass index, glycosylated haemoglobin (HbA1c), total cholesterol, triglyceride and high density (HDL) cholesterol were determined in all the patients. CCA-IMT determination was done by Carotid Doppler Ultrasonography. There were 120 (60%) males and 80 females (40%). Ages ranged from 28 to 79, mean 59.5 +/- 9.07 years. IMT on right side ranged from 0.4 mm to 2.4 mm, mean 0.88 mm and on left side mean IMT was 0.93 mm, range 0.5 mm to 2.5 mm. Duration of DM and BMI were correlated with IMT on both the sides (p < .05), statistically inverse correlation was seen with HDL cholesterol (p < .05). No significant correlation was seen with other variables. Duration of DM, BMI and HDL cholesterol were associated with CCA-IMT in patients with type 2 DM. No significant association was seen with other risk factors.
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This is an observational study carried out in 200 type 2 diabetic patients. Age, gender, duration of diabetes, history of ischaemic heart disease, hypertension and smoking was recorded. Body mass index, glycosylated haemoglobin (HbA1c), total cholesterol, triglyceride and high density (HDL) cholesterol were determined in all the patients. CCA-IMT determination was done by Carotid Doppler Ultrasonography. There were 120 (60%) males and 80 females (40%). Ages ranged from 28 to 79, mean 59.5 +/- 9.07 years. IMT on right side ranged from 0.4 mm to 2.4 mm, mean 0.88 mm and on left side mean IMT was 0.93 mm, range 0.5 mm to 2.5 mm. Duration of DM and BMI were correlated with IMT on both the sides (p < .05), statistically inverse correlation was seen with HDL cholesterol (p < .05). No significant correlation was seen with other variables. Duration of DM, BMI and HDL cholesterol were associated with CCA-IMT in patients with type 2 DM. No significant association was seen with other risk factors.</description><identifier>ISSN: 0030-9982</identifier><identifier>PMID: 19750850</identifier><identifier>CODEN: JJPAD4</identifier><language>eng</language><publisher>Karachi: Pakistan Medical Association</publisher><subject>Adult ; Aged ; Atherosclerosis (general aspects, experimental research) ; Biological and medical sciences ; Blood and lymphatic vessels ; Body Mass Index ; Cardiology. Vascular system ; Carotid Artery, Common - pathology ; Cholesterol, HDL ; Coronary Artery Disease - epidemiology ; Diabetes. Impaired glucose tolerance ; Diabetic Angiopathies - epidemiology ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Etiopathogenesis. Screening. Investigations. 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This is an observational study carried out in 200 type 2 diabetic patients. Age, gender, duration of diabetes, history of ischaemic heart disease, hypertension and smoking was recorded. Body mass index, glycosylated haemoglobin (HbA1c), total cholesterol, triglyceride and high density (HDL) cholesterol were determined in all the patients. CCA-IMT determination was done by Carotid Doppler Ultrasonography. There were 120 (60%) males and 80 females (40%). Ages ranged from 28 to 79, mean 59.5 +/- 9.07 years. IMT on right side ranged from 0.4 mm to 2.4 mm, mean 0.88 mm and on left side mean IMT was 0.93 mm, range 0.5 mm to 2.5 mm. Duration of DM and BMI were correlated with IMT on both the sides (p < .05), statistically inverse correlation was seen with HDL cholesterol (p < .05). No significant correlation was seen with other variables. Duration of DM, BMI and HDL cholesterol were associated with CCA-IMT in patients with type 2 DM. No significant association was seen with other risk factors.</description><subject>Adult</subject><subject>Aged</subject><subject>Atherosclerosis (general aspects, experimental research)</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Body Mass Index</subject><subject>Cardiology. Vascular system</subject><subject>Carotid Artery, Common - pathology</subject><subject>Cholesterol, HDL</subject><subject>Coronary Artery Disease - epidemiology</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Diabetic Angiopathies - epidemiology</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Etiopathogenesis. Screening. Investigations. 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Vascular system</topic><topic>Carotid Artery, Common - pathology</topic><topic>Cholesterol, HDL</topic><topic>Coronary Artery Disease - epidemiology</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Diabetic Angiopathies - epidemiology</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Etiopathogenesis. Screening. Investigations. Target tissue resistance</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Risk Factors</topic><topic>Tunica Intima - pathology</topic><topic>Tunica Media - pathology</topic><toplevel>online_resources</toplevel><creatorcontrib>MUJEEB-UR-REHMAN ABID BUTT</creatorcontrib><creatorcontrib>ZAKARIA, Manzar</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Pakistan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MUJEEB-UR-REHMAN ABID BUTT</au><au>ZAKARIA, Manzar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Common Carotid Intimal Medial Thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus</atitle><jtitle>Journal of the Pakistan Medical Association</jtitle><addtitle>J Pak Med Assoc</addtitle><date>2009-09</date><risdate>2009</risdate><volume>59</volume><issue>9</issue><spage>590</spage><epage>593</epage><pages>590-593</pages><issn>0030-9982</issn><coden>JJPAD4</coden><abstract>To determine the association of Common Carotid Intimal Medial Thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus. This is an observational study carried out in 200 type 2 diabetic patients. Age, gender, duration of diabetes, history of ischaemic heart disease, hypertension and smoking was recorded. Body mass index, glycosylated haemoglobin (HbA1c), total cholesterol, triglyceride and high density (HDL) cholesterol were determined in all the patients. CCA-IMT determination was done by Carotid Doppler Ultrasonography. There were 120 (60%) males and 80 females (40%). Ages ranged from 28 to 79, mean 59.5 +/- 9.07 years. IMT on right side ranged from 0.4 mm to 2.4 mm, mean 0.88 mm and on left side mean IMT was 0.93 mm, range 0.5 mm to 2.5 mm. Duration of DM and BMI were correlated with IMT on both the sides (p < .05), statistically inverse correlation was seen with HDL cholesterol (p < .05). No significant correlation was seen with other variables. Duration of DM, BMI and HDL cholesterol were associated with CCA-IMT in patients with type 2 DM. No significant association was seen with other risk factors.</abstract><cop>Karachi</cop><pub>Pakistan Medical Association</pub><pmid>19750850</pmid><tpages>4</tpages></addata></record>
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subjects	Adult Aged Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Body Mass Index Cardiology. Vascular system Carotid Artery, Common - pathology Cholesterol, HDL Coronary Artery Disease - epidemiology Diabetes. Impaired glucose tolerance Diabetic Angiopathies - epidemiology Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female General aspects Humans Male Medical sciences Middle Aged Risk Factors Tunica Intima - pathology Tunica Media - pathology
title	Association of Common Carotid Intimal Medial Thickness (CCA-IMT) with risk factors of atherosclerosis in patients with type 2 diabetes mellitus
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