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Detection of Immunoglobulin M Antibody to Hepatitis A Virus in Patients without Acute Hepatitis A: The Usefulness of Specific Immunoglobulin G Avidity
Immune cells may become activated during viral infections or immune diseases; thus, IgM antibodies directed against specific viral antigens can be detected because of nonspecific polyclonal activation of memory cells resulting from a previous infection with an unrelated agent [4-6]. However, many vi...
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Published in: | Clinical infectious diseases 2006-03, Vol.42 (6), p.887-888 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Immune cells may become activated during viral infections or immune diseases; thus, IgM antibodies directed against specific viral antigens can be detected because of nonspecific polyclonal activation of memory cells resulting from a previous infection with an unrelated agent [4-6]. However, many viral infections or immune diseases may cause hepatitis, and in some of these cases, antiHAV IgM may be detected because of polyclonal activation of the immune system. |
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ISSN: | 1058-4838 1537-6591 |
DOI: | 10.1086/500260 |