Loading…

Paradoxical Contributions of Non-Compacted and Compacted Segments to Global Left Ventricular Dysfunction in Isolated Left Ventricular Noncompaction

The pathophysiologic mechanisms of left ventricular (LV) dysfunction in isolated ventricular noncompaction (IVNC) remain unclear. Evaluating global and segmental systolic LV function in 65 patients with IVNC, this study found that normal wall motion was more common in noncompacted than in compacted...

Full description

Saved in:

Bibliographic Details
Published in:	The American journal of cardiology 2006-03, Vol.97 (5), p.738-741
Main Authors:	Lofiego, Carla, Biagini, Elena, Ferlito, Marinella, Pasquale, Ferdinando, Rocchi, Guido, Perugini, Enrica, Leone, Ornella, Bracchetti, Giovanni, Caliskan, Kadir, Branzi, Angelo, ten Cate, Folkert J., Rapezzi, Claudio
Format:	Article
Language:	English
Subjects:	Adult Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular disease Echocardiography, Doppler, Color Female Heart Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Male Medical sciences Middle Aged Observer Variation Stroke Volume Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - epidemiology Ventricular Dysfunction, Left - pathology Ventricular Dysfunction, Left - physiopathology
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by	cdi_FETCH-LOGICAL-c486t-bf51998cca37eb4def6b33295098b925b64334b4767557dc65ce56a4a68d95453
cites	cdi_FETCH-LOGICAL-c486t-bf51998cca37eb4def6b33295098b925b64334b4767557dc65ce56a4a68d95453
container_end_page	741
container_issue	5
container_start_page	738
container_title	The American journal of cardiology
container_volume	97
creator	Lofiego, Carla Biagini, Elena Ferlito, Marinella Pasquale, Ferdinando Rocchi, Guido Perugini, Enrica Leone, Ornella Bracchetti, Giovanni Caliskan, Kadir Branzi, Angelo ten Cate, Folkert J. Rapezzi, Claudio
description	The pathophysiologic mechanisms of left ventricular (LV) dysfunction in isolated ventricular noncompaction (IVNC) remain unclear. Evaluating global and segmental systolic LV function in 65 patients with IVNC, this study found that normal wall motion was more common in noncompacted than in compacted segments. The number of noncompacted segments per patient correlated positively with the LV ejection fraction and negatively with LV end-diastolic volume index. These paradoxical findings support the concept that noncompaction represents a marker of a more generalized (cardio)myopathy rather than the direct pathophysiologic substrate of this still little-understood disease.
doi_str_mv	10.1016/j.amjcard.2005.09.109
format	article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67677326</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002914905020072</els_id><sourcerecordid>67677326</sourcerecordid><originalsourceid>FETCH-LOGICAL-c486t-bf51998cca37eb4def6b33295098b925b64334b4767557dc65ce56a4a68d95453</originalsourceid><addsrcrecordid>eNqFkV2L1DAUhoMo7uzqT1CCoHcdk-ajzZUso64Lgwp-3IY0OZUMbTImrbi_wz-8KVMY0AuvwgnP--aQB6FnlGwpofL1YWvGgzXJbWtCxJaocq0eoA1tG1VRRdlDtCGE1JWiXF2gy5wPZaRUyMfogkquCOftBv35bJJx8be3ZsC7GKbku3nyMWQce_wxhmoXx6OxEzhsgsPn6Qv8GCFMGU8R3wyxK_k99BP-DkuJnQeT8Nu73M_BLn3YB3yb42CW7D9geciemgv6BD3qzZDh6XpeoW_v333dfaj2n25ud9f7yvJWTlXXC6pUa61hDXTcQS87xmoliGo7VYtOcsZ4xxvZCNE4K4UFIQ03snVKcMGu0KtT7zHFnzPkSY8-WxgGEyDOWcuSbFgtC_jiL_AQ5xTKbrpmhEnGBC-QOEE2xZwT9PqY_GjSnaZEL8r0Qa_K9KJME1WuVck9X8vnbgR3Tq2OCvByBUwulvpkgvX5zDWi2K5p4d6cOCh_9stD0tl6CBacT2An7aL_zyr3hza47Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>230363354</pqid></control><display><type>article</type><title>Paradoxical Contributions of Non-Compacted and Compacted Segments to Global Left Ventricular Dysfunction in Isolated Left Ventricular Noncompaction</title><source>ScienceDirect Journals</source><creator>Lofiego, Carla ; Biagini, Elena ; Ferlito, Marinella ; Pasquale, Ferdinando ; Rocchi, Guido ; Perugini, Enrica ; Leone, Ornella ; Bracchetti, Giovanni ; Caliskan, Kadir ; Branzi, Angelo ; ten Cate, Folkert J. ; Rapezzi, Claudio</creator><creatorcontrib>Lofiego, Carla ; Biagini, Elena ; Ferlito, Marinella ; Pasquale, Ferdinando ; Rocchi, Guido ; Perugini, Enrica ; Leone, Ornella ; Bracchetti, Giovanni ; Caliskan, Kadir ; Branzi, Angelo ; ten Cate, Folkert J. ; Rapezzi, Claudio</creatorcontrib><description>The pathophysiologic mechanisms of left ventricular (LV) dysfunction in isolated ventricular noncompaction (IVNC) remain unclear. Evaluating global and segmental systolic LV function in 65 patients with IVNC, this study found that normal wall motion was more common in noncompacted than in compacted segments. The number of noncompacted segments per patient correlated positively with the LV ejection fraction and negatively with LV end-diastolic volume index. These paradoxical findings support the concept that noncompaction represents a marker of a more generalized (cardio)myopathy rather than the direct pathophysiologic substrate of this still little-understood disease.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2005.09.109</identifier><identifier>PMID: 16490448</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Cardiology ; Cardiology. Vascular system ; Cardiovascular disease ; Echocardiography, Doppler, Color ; Female ; Heart ; Heart failure, cardiogenic pulmonary edema, cardiac enlargement ; Humans ; Male ; Medical sciences ; Middle Aged ; Observer Variation ; Stroke Volume ; Ventricular Dysfunction, Left - diagnostic imaging ; Ventricular Dysfunction, Left - epidemiology ; Ventricular Dysfunction, Left - pathology ; Ventricular Dysfunction, Left - physiopathology</subject><ispartof>The American journal of cardiology, 2006-03, Vol.97 (5), p.738-741</ispartof><rights>2006 Elsevier Inc.</rights><rights>2006 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. Mar 1, 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c486t-bf51998cca37eb4def6b33295098b925b64334b4767557dc65ce56a4a68d95453</citedby><cites>FETCH-LOGICAL-c486t-bf51998cca37eb4def6b33295098b925b64334b4767557dc65ce56a4a68d95453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17591321$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16490448$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lofiego, Carla</creatorcontrib><creatorcontrib>Biagini, Elena</creatorcontrib><creatorcontrib>Ferlito, Marinella</creatorcontrib><creatorcontrib>Pasquale, Ferdinando</creatorcontrib><creatorcontrib>Rocchi, Guido</creatorcontrib><creatorcontrib>Perugini, Enrica</creatorcontrib><creatorcontrib>Leone, Ornella</creatorcontrib><creatorcontrib>Bracchetti, Giovanni</creatorcontrib><creatorcontrib>Caliskan, Kadir</creatorcontrib><creatorcontrib>Branzi, Angelo</creatorcontrib><creatorcontrib>ten Cate, Folkert J.</creatorcontrib><creatorcontrib>Rapezzi, Claudio</creatorcontrib><title>Paradoxical Contributions of Non-Compacted and Compacted Segments to Global Left Ventricular Dysfunction in Isolated Left Ventricular Noncompaction</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>The pathophysiologic mechanisms of left ventricular (LV) dysfunction in isolated ventricular noncompaction (IVNC) remain unclear. Evaluating global and segmental systolic LV function in 65 patients with IVNC, this study found that normal wall motion was more common in noncompacted than in compacted segments. The number of noncompacted segments per patient correlated positively with the LV ejection fraction and negatively with LV end-diastolic volume index. These paradoxical findings support the concept that noncompaction represents a marker of a more generalized (cardio)myopathy rather than the direct pathophysiologic substrate of this still little-understood disease.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular disease</subject><subject>Echocardiography, Doppler, Color</subject><subject>Female</subject><subject>Heart</subject><subject>Heart failure, cardiogenic pulmonary edema, cardiac enlargement</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Observer Variation</subject><subject>Stroke Volume</subject><subject>Ventricular Dysfunction, Left - diagnostic imaging</subject><subject>Ventricular Dysfunction, Left - epidemiology</subject><subject>Ventricular Dysfunction, Left - pathology</subject><subject>Ventricular Dysfunction, Left - physiopathology</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNqFkV2L1DAUhoMo7uzqT1CCoHcdk-ajzZUso64Lgwp-3IY0OZUMbTImrbi_wz-8KVMY0AuvwgnP--aQB6FnlGwpofL1YWvGgzXJbWtCxJaocq0eoA1tG1VRRdlDtCGE1JWiXF2gy5wPZaRUyMfogkquCOftBv35bJJx8be3ZsC7GKbku3nyMWQce_wxhmoXx6OxEzhsgsPn6Qv8GCFMGU8R3wyxK_k99BP-DkuJnQeT8Nu73M_BLn3YB3yb42CW7D9geciemgv6BD3qzZDh6XpeoW_v333dfaj2n25ud9f7yvJWTlXXC6pUa61hDXTcQS87xmoliGo7VYtOcsZ4xxvZCNE4K4UFIQ03snVKcMGu0KtT7zHFnzPkSY8-WxgGEyDOWcuSbFgtC_jiL_AQ5xTKbrpmhEnGBC-QOEE2xZwT9PqY_GjSnaZEL8r0Qa_K9KJME1WuVck9X8vnbgR3Tq2OCvByBUwulvpkgvX5zDWi2K5p4d6cOCh_9stD0tl6CBacT2An7aL_zyr3hza47Q</recordid><startdate>20060301</startdate><enddate>20060301</enddate><creator>Lofiego, Carla</creator><creator>Biagini, Elena</creator><creator>Ferlito, Marinella</creator><creator>Pasquale, Ferdinando</creator><creator>Rocchi, Guido</creator><creator>Perugini, Enrica</creator><creator>Leone, Ornella</creator><creator>Bracchetti, Giovanni</creator><creator>Caliskan, Kadir</creator><creator>Branzi, Angelo</creator><creator>ten Cate, Folkert J.</creator><creator>Rapezzi, Claudio</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20060301</creationdate><title>Paradoxical Contributions of Non-Compacted and Compacted Segments to Global Left Ventricular Dysfunction in Isolated Left Ventricular Noncompaction</title><author>Lofiego, Carla ; Biagini, Elena ; Ferlito, Marinella ; Pasquale, Ferdinando ; Rocchi, Guido ; Perugini, Enrica ; Leone, Ornella ; Bracchetti, Giovanni ; Caliskan, Kadir ; Branzi, Angelo ; ten Cate, Folkert J. ; Rapezzi, Claudio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c486t-bf51998cca37eb4def6b33295098b925b64334b4767557dc65ce56a4a68d95453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular disease</topic><topic>Echocardiography, Doppler, Color</topic><topic>Female</topic><topic>Heart</topic><topic>Heart failure, cardiogenic pulmonary edema, cardiac enlargement</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Observer Variation</topic><topic>Stroke Volume</topic><topic>Ventricular Dysfunction, Left - diagnostic imaging</topic><topic>Ventricular Dysfunction, Left - epidemiology</topic><topic>Ventricular Dysfunction, Left - pathology</topic><topic>Ventricular Dysfunction, Left - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lofiego, Carla</creatorcontrib><creatorcontrib>Biagini, Elena</creatorcontrib><creatorcontrib>Ferlito, Marinella</creatorcontrib><creatorcontrib>Pasquale, Ferdinando</creatorcontrib><creatorcontrib>Rocchi, Guido</creatorcontrib><creatorcontrib>Perugini, Enrica</creatorcontrib><creatorcontrib>Leone, Ornella</creatorcontrib><creatorcontrib>Bracchetti, Giovanni</creatorcontrib><creatorcontrib>Caliskan, Kadir</creatorcontrib><creatorcontrib>Branzi, Angelo</creatorcontrib><creatorcontrib>ten Cate, Folkert J.</creatorcontrib><creatorcontrib>Rapezzi, Claudio</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lofiego, Carla</au><au>Biagini, Elena</au><au>Ferlito, Marinella</au><au>Pasquale, Ferdinando</au><au>Rocchi, Guido</au><au>Perugini, Enrica</au><au>Leone, Ornella</au><au>Bracchetti, Giovanni</au><au>Caliskan, Kadir</au><au>Branzi, Angelo</au><au>ten Cate, Folkert J.</au><au>Rapezzi, Claudio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Paradoxical Contributions of Non-Compacted and Compacted Segments to Global Left Ventricular Dysfunction in Isolated Left Ventricular Noncompaction</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2006-03-01</date><risdate>2006</risdate><volume>97</volume><issue>5</issue><spage>738</spage><epage>741</epage><pages>738-741</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>The pathophysiologic mechanisms of left ventricular (LV) dysfunction in isolated ventricular noncompaction (IVNC) remain unclear. Evaluating global and segmental systolic LV function in 65 patients with IVNC, this study found that normal wall motion was more common in noncompacted than in compacted segments. The number of noncompacted segments per patient correlated positively with the LV ejection fraction and negatively with LV end-diastolic volume index. These paradoxical findings support the concept that noncompaction represents a marker of a more generalized (cardio)myopathy rather than the direct pathophysiologic substrate of this still little-understood disease.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>16490448</pmid><doi>10.1016/j.amjcard.2005.09.109</doi><tpages>4</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 0002-9149
ispartof	The American journal of cardiology, 2006-03, Vol.97 (5), p.738-741
issn	0002-9149 1879-1913
language	eng
recordid	cdi_proquest_miscellaneous_67677326
source	ScienceDirect Journals
subjects	Adult Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular disease Echocardiography, Doppler, Color Female Heart Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Male Medical sciences Middle Aged Observer Variation Stroke Volume Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - epidemiology Ventricular Dysfunction, Left - pathology Ventricular Dysfunction, Left - physiopathology
title	Paradoxical Contributions of Non-Compacted and Compacted Segments to Global Left Ventricular Dysfunction in Isolated Left Ventricular Noncompaction
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T07%3A55%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Paradoxical%20Contributions%20of%20Non-Compacted%20and%20Compacted%20Segments%20to%20Global%20Left%20Ventricular%20Dysfunction%20in%20Isolated%20Left%20Ventricular%20Noncompaction&rft.jtitle=The%20American%20journal%20of%20cardiology&rft.au=Lofiego,%20Carla&rft.date=2006-03-01&rft.volume=97&rft.issue=5&rft.spage=738&rft.epage=741&rft.pages=738-741&rft.issn=0002-9149&rft.eissn=1879-1913&rft.coden=AJCDAG&rft_id=info:doi/10.1016/j.amjcard.2005.09.109&rft_dat=%3Cproquest_cross%3E67677326%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c486t-bf51998cca37eb4def6b33295098b925b64334b4767557dc65ce56a4a68d95453%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=230363354&rft_id=info:pmid/16490448&rfr_iscdi=true