Biofunctional magnetic nanoparticles for protein separation and pathogen detection

Recent successful syntheses of monodispersed magnetic nanoparticles have offered a unique opportunity to control and probe biological interactions using magnetic force. This paper highlights a general strategy to generate biofunctional magnetic nanoparticles, illustrates applications for these nanop...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2006-01 (9), p.941-949
Main Authors: Gu, Hongwei, Xu, Keming, Xu, Chenjie, Xu, Bing
Format: Article
Language:English
Subjects:
Infection - diagnosis
Infection - microbiology
Magnetics
Nanoparticles - chemistry
Nanoparticles - microbiology
Nanoparticles - ultrastructure
Nanotechnology - methods
Proteins - chemistry
Proteins - isolation & purification
Sensitivity and Specificity
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Summary:Recent successful syntheses of monodispersed magnetic nanoparticles have offered a unique opportunity to control and probe biological interactions using magnetic force. This paper highlights a general strategy to generate biofunctional magnetic nanoparticles, illustrates applications for these nanoparticles in protein separation and pathogen detection, and analyzes the high sensitivity and high selectivity achieved by this system.
ISSN:1359-7345
1364-548X
DOI:10.1039/b514130c