CyNodal, the Japanese newt nodal-related gene, is expressed in the left side of the lateral plate mesoderm and diencephalon

The nodal and nodal-related genes play fundamental roles during deuterostome left–right axis formation. Several of these genes show left-sided expression in the lateral plate mesoderm and brain region. We have isolated the nodal-related gene, CyNodal, from Cynops pyrrhogaster. CyNodal mRNA is detect...

Full description

Saved in:
Bibliographic Details
Published in:Gene Expression Patterns 2006-03, Vol.6 (3), p.294-298
Main Authors: Ito, Yuzuru, Oinuma, Tsutomu, Takano, Kazuhiro, Komazaki, Shinji, Obata, Shuichi, Asashima, Makoto
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Body Patterning - genetics
Body Patterning - physiology
Conserved Sequence
Cynops pyrrhogaster
Cysteine - chemistry
Diencephalon
Diencephalon - metabolism
DNA, Complementary - genetics
DNA, Complementary - isolation & purification
Embryo, Nonmammalian
Evolution, Molecular
Female
Gene Expression Regulation, Developmental
In Situ Hybridization
Lateral plate mesoderm
Left–right asymmetry
Mesoderm - metabolism
Molecular Sequence Data
Nodal
Proteins - genetics
Salamandridae - embryology
Salamandridae - genetics
Salamandridae - metabolism
Sequence Homology, Amino Acid
Staining and Labeling
Xnr1
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The nodal and nodal-related genes play fundamental roles during deuterostome left–right axis formation. Several of these genes show left-sided expression in the lateral plate mesoderm and brain region. We have isolated the nodal-related gene, CyNodal, from Cynops pyrrhogaster. CyNodal mRNA is detected at the marginal zone and left side of several tissues. The left-sideness of CyNodal mRNA expression is highly conserved throughout vertebrate evolution. However, CyNodal mRNA expression shows little variation from the Xenopus nodal-related gene 1, in that CyNodal gene expression in the left lateral plate mesoderm shifts from posterior to anterior at least twice.
ISSN:1567-133X
1872-7298
DOI:10.1016/j.modgep.2005.07.008