Diversity of Endodontic Microbiota Revisited

Although fungi, archaea, and viruses contribute to the microbial diversity in endodontic infections, bacteria are the most common micro-organisms occurring in these infections. Datasets from culture and molecular studies, integrated here for the first time, showed that over 460 unique bacterial taxa...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Dental Research 2009-11, Vol.88 (11), p.969-981
Main Authors: Siqueira, J.F., Rôças, I.N.
Format: Article
Language:English
Subjects:
Actinobacteria - classification
Archaea - classification
Bacteria
Bacteria - classification
Bacterial Infections - classification
Bacteriological Techniques
Bacteroidetes - classification
Dental Pulp Cavity - microbiology
Dental Pulp Diseases - microbiology
Dental Pulp Necrosis - microbiology
Dentistry
Disease
Fungi
Humans
Infections
Microbiota
Molecular Biology
Pathogenesis
Proteobacteria - classification
Recurrence
RNA, Bacterial - analysis
RNA, Ribosomal, 16S - analysis
Root Canal Therapy
Species richness
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Although fungi, archaea, and viruses contribute to the microbial diversity in endodontic infections, bacteria are the most common micro-organisms occurring in these infections. Datasets from culture and molecular studies, integrated here for the first time, showed that over 460 unique bacterial taxa belonging to 100 genera and 9 phyla have been identified in different types of endodontic infections. The phyla with the highest species richness were Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria. Diversity varies significantly according to the type of infection. Overall, more taxa have been disclosed by molecular studies than by culture. Many cultivable and as-yet-uncultivated phylotypes have emerged as candidate pathogens based on detection in several studies and/or high prevalence. Now that a comprehensive inventory of the endodontic microbial taxa has been established, future research should focus on the association with different disease conditions, functional roles in the community, and susceptibility to antimicrobial treatment procedures.
ISSN:0022-0345
1544-0591
DOI:10.1177/0022034509346549