Metachronous bilateral pleomorphic adenoma of the parotid gland

Bilateral salivary gland tumors are very rare, accounting for 3% of all parotid gland tumors. Although the most common tumor with bilateral development is the Warthin tumor, pleomorphic adenomas (PA) have been diagnosed simultaneously as well, but in a smaller incidence. Because of this, the prevale...

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Published in:Oral surgery, oral medicine, oral pathology, oral radiology and endodontics oral medicine, oral pathology, oral radiology and endodontics, 2006-03, Vol.101 (3), p.333-338
Main Authors: DA SILVA, Sindeval José, TADEU COSTA, Gabriel, BRANT FILHO, Adalberto Caldeira, ROGERIO FARIA, Paulo, MOTA LOYOLA, Adriano
Format: Article
Language:English
Subjects:
Adenoma, Pleomorphic - pathology
Adenoma, Pleomorphic - surgery
Biological and medical sciences
Dentistry
Facial Nerve - surgery
Female
Humans
Medical sciences
Middle Aged
Neoplasms, Multiple Primary - pathology
Otorhinolaryngology. Stomatology
Parotid Gland - surgery
Parotid Neoplasms - pathology
Parotid Neoplasms - surgery
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Summary:Bilateral salivary gland tumors are very rare, accounting for 3% of all parotid gland tumors. Although the most common tumor with bilateral development is the Warthin tumor, pleomorphic adenomas (PA) have been diagnosed simultaneously as well, but in a smaller incidence. Because of this, the prevalence, etiology, pathogenesis, and behavior of the PA in this context are poorly understood. We present a case of bilateral metachronous PA affecting the parotid gland in a 63-year-old woman. Clinically, the lesions presented with similar aspects as seen in cases of solitary PA with slow-growing asymptomatic nodule. Both lesions were diagnosed by fine-needle aspiration biopsy at an interval of 2 years between them. A total and superficial parotidectomy for left and right tumors, respectively, was performed. Only on the left side some facial nerve branches were removed that induced partial paralysis in the patient. A review of the pertinent literature is included.
ISSN:1079-2104
1528-395X
DOI:10.1016/j.tripleo.2005.07.025