How much and for how long does the neonatal myocardium suffer from mild perinatal asphyxia?

Cardiac troponins can be useful in monitoring cardiac injury following perinatal distress. We report here an increase of cardiac troponin I (cTnI) to 2.84 μg/l at 3 weeks (age-related median: 0.07 μg/l) followed by normalization in a newborn with an uneventful clinical course after resuscitation at...

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Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2005-01, Vol.17 (1), p.85-86
Main Authors: Cavalli, C, Dorizzi, RM, Lanzoni, L, Caputo, M, Biban, P
Format: Article
Language:English
Subjects:
Asphyxia Neonatorum - complications
Asphyxia Neonatorum - metabolism
Asphyxia Neonatorum - therapy
cardiac troponins
Echocardiography
Female
Humans
Infant, Newborn
Myocardial Ischemia - diagnostic imaging
Myocardial Ischemia - etiology
Myocardial Ischemia - metabolism
Myocardium - metabolism
Parturition
Perinatal asphyxia
Resuscitation
Time Factors
transient myocardial ischemia of the newborn
Troponin I - metabolism
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Summary:Cardiac troponins can be useful in monitoring cardiac injury following perinatal distress. We report here an increase of cardiac troponin I (cTnI) to 2.84 μg/l at 3 weeks (age-related median: 0.07 μg/l) followed by normalization in a newborn with an uneventful clinical course after resuscitation at birth. Serial echocardiographs showed normal cardiac function. Such a time course of cTnI, not previously reported, could be due to either a greater sensitivity of biochemical markers than of instrumental tools or birth asphyxia. Larger studies are needed.
ISSN:1476-7058
1476-4954
DOI:10.1080/14767050400013438