Pancreatic carcinoma versus chronic focal pancreatitis: contrast-enhanced power Doppler ultrasonography findings

We assessed the potential usefulness of contrast-enhanced power Doppler ultrasonography (US) for differentiating pancreatic carcinoma from chronic focal pancreatitis. Twenty-six consecutive patients with ductal carcinoma (n=16) and chronic focal pancreatitis (n=10) underwent power Doppler US examina...

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Bibliographic Details
Published in:Abdominal imaging 2005-03, Vol.30 (2), p.222-227
Main Authors: SCIALPI, M, MIDIRI, M, BARTOLOTTA, T. V, CAZZOLLA, M. P, ROTONDO, A, RESTA, M. C, LAGALLA, R, CARDINALE, A. E
Format: Article
Language:English
Subjects:
Adenocarcinoma - blood supply
Adenocarcinoma - diagnostic imaging
Adenocarcinoma - physiopathology
Adult
Aged
Biological and medical sciences
Blood Flow Velocity - physiology
Cardiovascular system
Chronic Disease
Contrast Media - administration & dosage
Diagnosis, Differential
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Injections, Intravenous
Investigative techniques, diagnostic techniques (general aspects)
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Other diseases. Semiology
Pancreatic Neoplasms - blood supply
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - physiopathology
Pancreatitis - diagnostic imaging
Pancreatitis - physiopathology
Polysaccharides - administration & dosage
Retrospective Studies
Tumors
Ultrasonic investigative techniques
Ultrasonography, Doppler - methods
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Summary:We assessed the potential usefulness of contrast-enhanced power Doppler ultrasonography (US) for differentiating pancreatic carcinoma from chronic focal pancreatitis. Twenty-six consecutive patients with ductal carcinoma (n=16) and chronic focal pancreatitis (n=10) underwent power Doppler US examinations before and after intravenous injection of an air-based contrast agent (Levovist, Schering, Berlin, Germany). Final diagnosis was obtained by surgery in all patients. The following parameters before and after intravenous administration of contrast agent were evaluated for each lesion: number, morphology and course of the vessels within the lesion and time to maximum detectable enhancement. Number of the lesion vessels and time to maximum enhancement for each lesion were compared by with Student t test. After injection of contrast agent, nine of 16 (56.2%) carcinomas showed a larger total number of vessels (p
ISSN:0942-8925
2366-004X
1432-0509
2366-0058
DOI:10.1007/s00261-004-0229-9