Sildenafil as treatment for Human Immunodeficiency Virus‐related pulmonary hypertension in a child

:  Human Immunodeficiency Virus (HIV)‐related pulmonary hypertension is a relatively rare disease that can affect HIV sufferers. This is almost always associated with a poor outcome and death. An 18 month‐old girl, probably the youngest on record, was diagnosed to have pulmonary hypertension (PHT) a...

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Published in:Journal of paediatrics and child health 2006-03, Vol.42 (3), p.147-148
Main Authors: Wong, Abdul Rahim, Rasool, Aida Hanum G., Abidin, Nik Zainal, Noor, Abdul Rahmand, Quah, Ban Seng
Format: Article
Language:English
Subjects:
Cardiomegaly - complications
Enzyme-Linked Immunosorbent Assay
Female
HIV
HIV Infections - complications
Human Immunodeficiency Virus
Humans
Hypertension, Pulmonary - drug therapy
Hypertension, Pulmonary - etiology
Infant
Infants
Piperazines - administration & dosage
Piperazines - therapeutic use
Pulmonary hypertension
Purines
Sildenafil
Sildenafil Citrate
Sulfones
Treatment Outcome
Vasodilator Agents - administration & dosage
Vasodilator Agents - therapeutic use
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Summary::  Human Immunodeficiency Virus (HIV)‐related pulmonary hypertension is a relatively rare disease that can affect HIV sufferers. This is almost always associated with a poor outcome and death. An 18 month‐old girl, probably the youngest on record, was diagnosed to have pulmonary hypertension (PHT) and retrospectively found to have HIV infection. Sildenafil was used to control her PHT and she remains alive even after 2 years.
ISSN:1034-4810
1440-1754
DOI:10.1111/j.1440-1754.2006.00816.x