Relation of the use of lipid-lowering medications prior to percutaneous coronary intervention to the incidence of intraprocedural adverse angiographic events

The use of lipid-lowering medications at the time of percutaneouscoronary intervention (PCI) has been shown to have a favorable effect on rates of cardiac enzyme elevation and major adverse cardiac events (MACEs), but the effect of these medications on angiographically identifiable intraprocedural c...

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Bibliographic Details
Published in:The American journal of cardiology 2005-04, Vol.95 (8), p.978-980
Main Authors: FERGUSON, Michael A, ROMICK, Benjamin G, CARTER, Luther I, DE GEARE, Vincent S
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary - adverse effects
Biological and medical sciences
Cardiology. Vascular system
Coronary Angiography
Drug therapy
Female
Heart
Humans
Hyperlipidemias - drug therapy
Hypolipidemic Agents - administration & dosage
Hypolipidemic Agents - therapeutic use
Intraoperative Period
Lipids
Male
Medical sciences
Middle Aged
Multivariate Analysis
Odds Ratio
Retrospective Studies
Surgery
Treatment Outcome
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Description
Summary:The use of lipid-lowering medications at the time of percutaneouscoronary intervention (PCI) has been shown to have a favorable effect on rates of cardiac enzyme elevation and major adverse cardiac events (MACEs), but the effect of these medications on angiographically identifiable intraprocedural coronary events during PCI has not previously been investigated. A retrospective review of 81 patients was performed and demonstrated that the use of lipid-lowering medications at the time of PCI was associated with a reduced incidence of angiographically identifiable intraprocedural events (odds ratio 0.13, 95% confidence interval 0.04 to 0.40). A multivariate analysis revealed that lipid-lowering medications and hyperlipidemia did not predict MACEs independent of the occurrence of these angiographic events.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.12.040