Effects of supplemental cystine or methionine on growth and lifespan of stroke-prone spontaneously hypertensive rats

Stroke-prone spontaneously hypertensive (SHRSP) rats are considered a suitable model for studying the effects of dietary and other environmental factors on human essential hypertension and haemorrhagic stroke. To investigate the suitability of a control diet for this strain of rats, we studied the e...

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Bibliographic Details
Published in:British journal of nutrition 2006-03, Vol.95 (3), p.443-447
Main Authors: Gilani, G. Sarwar, Ratnayake, W. M. Nimal, Peace, Robert W., Muller, Rudolf
Format: Article
Language:English
Subjects:
Alcohol
Amino acids
animal disease models
Animal models
Animals
Biological and medical sciences
Caseins - administration & dosage
cystine
Cystine - administration & dosage
Diet
dietary protein
Dietary Proteins - administration & dosage
Dietary Supplements
Drinking water
Eating
Environmental factors
epidemiological studies
experimental diets
Feeding. Feeding behavior
Food
Fundamental and applied biological sciences. Psychology
Hypertension
Hypertension - physiopathology
Laboratory animals
Life span
Longevity - drug effects
Male
metabolizable energy
methionine
Methionine - administration & dosage
Models, Animal
nutrient availability
Nutrition research
portal hypertension
protein supplements
Proteins
Rats
Rats, Inbred SHR
Research methodology
risk factors
Short Communication
Soybean Proteins - administration & dosage
stroke
Stroke - physiopathology
Sulfur
Survival
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Weight Gain - drug effects
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Summary:Stroke-prone spontaneously hypertensive (SHRSP) rats are considered a suitable model for studying the effects of dietary and other environmental factors on human essential hypertension and haemorrhagic stroke. To investigate the suitability of a control diet for this strain of rats, we studied the effects of supplementing casein and soya protein isolate (SPI) with two sulphur amino acids (methionine and cystine) on the growth and lifespan of SHRSP rats. The source of dietary protein and the type of supplemental sulphur amino acid had significant (P
ISSN:0007-1145
1475-2662
DOI:10.1079/BJN20051712