Loading…

Usefulness of Myocardial Contrast Echocardiography Early After Acute Myocardial Infarction

Objectives: (1) Evaluate wall motion and perfusion abnormalities after reperfusion therapy of the culprit lesion, (2) delineate the ability of myocardial contrast echocardiography (MCE) to evaluate the microvasculature after reperfusion, in order to distinguish between stunning and necrosis in the r...

Full description

Saved in:
Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2006-03, Vol.23 (3), p.208-217
Main Authors: Cianciulli, Tomás F., Lax, Jorge A., Beck, Martín A., Masoli, Osvaldo H., Redruello, Marcela F., Saccheri, María C., Guevara, Eduardo, Gagliardi, Juan A., Dorelle, Adriana N., Prezioso, Horacio A.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c4050-cca621a970c2d1309b29829402df555205c2675618e14051fc4631342f8202e03
cites cdi_FETCH-LOGICAL-c4050-cca621a970c2d1309b29829402df555205c2675618e14051fc4631342f8202e03
container_end_page 217
container_issue 3
container_start_page 208
container_title Echocardiography (Mount Kisco, N.Y.)
container_volume 23
creator Cianciulli, Tomás F.
Lax, Jorge A.
Beck, Martín A.
Masoli, Osvaldo H.
Redruello, Marcela F.
Saccheri, María C.
Guevara, Eduardo
Gagliardi, Juan A.
Dorelle, Adriana N.
Prezioso, Horacio A.
description Objectives: (1) Evaluate wall motion and perfusion abnormalities after reperfusion therapy of the culprit lesion, (2) delineate the ability of myocardial contrast echocardiography (MCE) to evaluate the microvasculature after reperfusion, in order to distinguish between stunning and necrosis in the risk area. Methods: We analyzed 446 segments from 28 patients, 10 normal controls (160 segments), and 18 with a first AMI (286 segments). MCE was obtained with Optison and a two‐dimensional echocardiography was performed at 3 months post acute myocardial infarction (AMI). Results: In the group with AMI, we analyzed 286 segments, of which 107 had wall motion abnormalities (WMA) related to the culprit artery. Two subgroups were identified: Group I with WMA and normal perfusion (50 segments, 47%) and Group II with WMA and perfusion defects (57 segments, 53%). According to the 2D echocardiogram at 3 months, they were further subdivided into: Group IA: with wall motion improvement (stunning): 18 segments, 36%, Group IB: without wall motion improvement: 32 segments, 64%, Group IIA: with wall motion improvement: 12 segments, 21%, Group IIB: without wall motion improvement (necrosis): 45 segments, 79%. Conclusions: (1) The presence of myocardial perfusion in segments with WMA immediately after AMI reperfusion therapy predicts viability in most patients. Conversely, the lack of perfusion is not an absolute indicator of the presence of necrosis. (2) Perfusion defects allow to detect patients with thrombolysis in myocardial infarction (TIMI) 3 flow and “no‐reflow” phenomenon who will not show improved wall motion in the 2D echocardiogram. However, some patients with initial no‐reflow could have microvascular stunning and their regional contractile function will normalize after a recovery period.
doi_str_mv 10.1111/j.1540-8175.2006.00190.x
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67734549</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67734549</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4050-cca621a970c2d1309b29829402df555205c2675618e14051fc4631342f8202e03</originalsourceid><addsrcrecordid>eNqNkE1P3DAQhq2qqCy0f6HKiVvSmYmdjwOH1Wr50gIHQEi9WMZrl2yzydZOxObf10tWwBFfbI3fZ2b0MBYhJBjOr1WCgkNcYC4SAsgSACwh2X5hk7ePr2wCOaeYCqJDduT9CgByRP6NHWImiKclTtjvB29sXzfG-6i10fXQauWWlaqjWdt0Tvkumuvnsdj-cWrzPERz5eohmtrOuGiq-858xC4bq5zuqrb5zg6sqr35sb-P2cPZ_H52ES9uzy9n00WsOQiItVYZoSpz0LTEFMonKgsqOdDSCiEIhKYsFxkWBgOAVvMsxZSTLQjIQHrMTsa-G9f-643v5Lry2tS1akzbe5nlecoFL0OwGIPatd47Y-XGVWvlBokgd17lSu70yZ0-ufMqX73KbUB_7mf0T2uzfAf3IkPgdAy8VLUZPt1YzmcXt-EV-HjkK9-Z7Ruv3N-wfxqox5tzSYT8enH1KO_S_6zNlD4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67734549</pqid></control><display><type>article</type><title>Usefulness of Myocardial Contrast Echocardiography Early After Acute Myocardial Infarction</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><creator>Cianciulli, Tomás F. ; Lax, Jorge A. ; Beck, Martín A. ; Masoli, Osvaldo H. ; Redruello, Marcela F. ; Saccheri, María C. ; Guevara, Eduardo ; Gagliardi, Juan A. ; Dorelle, Adriana N. ; Prezioso, Horacio A.</creator><creatorcontrib>Cianciulli, Tomás F. ; Lax, Jorge A. ; Beck, Martín A. ; Masoli, Osvaldo H. ; Redruello, Marcela F. ; Saccheri, María C. ; Guevara, Eduardo ; Gagliardi, Juan A. ; Dorelle, Adriana N. ; Prezioso, Horacio A.</creatorcontrib><description>Objectives: (1) Evaluate wall motion and perfusion abnormalities after reperfusion therapy of the culprit lesion, (2) delineate the ability of myocardial contrast echocardiography (MCE) to evaluate the microvasculature after reperfusion, in order to distinguish between stunning and necrosis in the risk area. Methods: We analyzed 446 segments from 28 patients, 10 normal controls (160 segments), and 18 with a first AMI (286 segments). MCE was obtained with Optison and a two‐dimensional echocardiography was performed at 3 months post acute myocardial infarction (AMI). Results: In the group with AMI, we analyzed 286 segments, of which 107 had wall motion abnormalities (WMA) related to the culprit artery. Two subgroups were identified: Group I with WMA and normal perfusion (50 segments, 47%) and Group II with WMA and perfusion defects (57 segments, 53%). According to the 2D echocardiogram at 3 months, they were further subdivided into: Group IA: with wall motion improvement (stunning): 18 segments, 36%, Group IB: without wall motion improvement: 32 segments, 64%, Group IIA: with wall motion improvement: 12 segments, 21%, Group IIB: without wall motion improvement (necrosis): 45 segments, 79%. Conclusions: (1) The presence of myocardial perfusion in segments with WMA immediately after AMI reperfusion therapy predicts viability in most patients. Conversely, the lack of perfusion is not an absolute indicator of the presence of necrosis. (2) Perfusion defects allow to detect patients with thrombolysis in myocardial infarction (TIMI) 3 flow and “no‐reflow” phenomenon who will not show improved wall motion in the 2D echocardiogram. However, some patients with initial no‐reflow could have microvascular stunning and their regional contractile function will normalize after a recovery period.</description><identifier>ISSN: 0742-2822</identifier><identifier>EISSN: 1540-8175</identifier><identifier>DOI: 10.1111/j.1540-8175.2006.00190.x</identifier><identifier>PMID: 16524391</identifier><language>eng</language><publisher>350 Main St , Malden , MA 02148 , USA , and PO Box 1354, Garsington Rd , Oxford OX4 2DQ , UK and PO Box 378 Carlton South , 3053 Victoria , Australia: Blackwell Publishing Inc</publisher><subject>acute myocardial infarction ; Adult ; Aged ; Aged, 80 and over ; Albumins ; Case-Control Studies ; Contrast Media ; Echocardiography ; Female ; Fluorocarbons ; Humans ; Male ; microcirculation ; Middle Aged ; myocardial contrast echocardiography ; Myocardial Infarction - diagnostic imaging ; Myocardial Infarction - therapy ; Myocardial Reperfusion ; Myocardial Stunning - diagnostic imaging ; Necrosis ; Prospective Studies ; reperfusion ; stunning ; Thrombolytic Therapy ; Time Factors</subject><ispartof>Echocardiography (Mount Kisco, N.Y.), 2006-03, Vol.23 (3), p.208-217</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4050-cca621a970c2d1309b29829402df555205c2675618e14051fc4631342f8202e03</citedby><cites>FETCH-LOGICAL-c4050-cca621a970c2d1309b29829402df555205c2675618e14051fc4631342f8202e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16524391$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cianciulli, Tomás F.</creatorcontrib><creatorcontrib>Lax, Jorge A.</creatorcontrib><creatorcontrib>Beck, Martín A.</creatorcontrib><creatorcontrib>Masoli, Osvaldo H.</creatorcontrib><creatorcontrib>Redruello, Marcela F.</creatorcontrib><creatorcontrib>Saccheri, María C.</creatorcontrib><creatorcontrib>Guevara, Eduardo</creatorcontrib><creatorcontrib>Gagliardi, Juan A.</creatorcontrib><creatorcontrib>Dorelle, Adriana N.</creatorcontrib><creatorcontrib>Prezioso, Horacio A.</creatorcontrib><title>Usefulness of Myocardial Contrast Echocardiography Early After Acute Myocardial Infarction</title><title>Echocardiography (Mount Kisco, N.Y.)</title><addtitle>Echocardiography</addtitle><description>Objectives: (1) Evaluate wall motion and perfusion abnormalities after reperfusion therapy of the culprit lesion, (2) delineate the ability of myocardial contrast echocardiography (MCE) to evaluate the microvasculature after reperfusion, in order to distinguish between stunning and necrosis in the risk area. Methods: We analyzed 446 segments from 28 patients, 10 normal controls (160 segments), and 18 with a first AMI (286 segments). MCE was obtained with Optison and a two‐dimensional echocardiography was performed at 3 months post acute myocardial infarction (AMI). Results: In the group with AMI, we analyzed 286 segments, of which 107 had wall motion abnormalities (WMA) related to the culprit artery. Two subgroups were identified: Group I with WMA and normal perfusion (50 segments, 47%) and Group II with WMA and perfusion defects (57 segments, 53%). According to the 2D echocardiogram at 3 months, they were further subdivided into: Group IA: with wall motion improvement (stunning): 18 segments, 36%, Group IB: without wall motion improvement: 32 segments, 64%, Group IIA: with wall motion improvement: 12 segments, 21%, Group IIB: without wall motion improvement (necrosis): 45 segments, 79%. Conclusions: (1) The presence of myocardial perfusion in segments with WMA immediately after AMI reperfusion therapy predicts viability in most patients. Conversely, the lack of perfusion is not an absolute indicator of the presence of necrosis. (2) Perfusion defects allow to detect patients with thrombolysis in myocardial infarction (TIMI) 3 flow and “no‐reflow” phenomenon who will not show improved wall motion in the 2D echocardiogram. However, some patients with initial no‐reflow could have microvascular stunning and their regional contractile function will normalize after a recovery period.</description><subject>acute myocardial infarction</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Albumins</subject><subject>Case-Control Studies</subject><subject>Contrast Media</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Fluorocarbons</subject><subject>Humans</subject><subject>Male</subject><subject>microcirculation</subject><subject>Middle Aged</subject><subject>myocardial contrast echocardiography</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>Myocardial Infarction - therapy</subject><subject>Myocardial Reperfusion</subject><subject>Myocardial Stunning - diagnostic imaging</subject><subject>Necrosis</subject><subject>Prospective Studies</subject><subject>reperfusion</subject><subject>stunning</subject><subject>Thrombolytic Therapy</subject><subject>Time Factors</subject><issn>0742-2822</issn><issn>1540-8175</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNqNkE1P3DAQhq2qqCy0f6HKiVvSmYmdjwOH1Wr50gIHQEi9WMZrl2yzydZOxObf10tWwBFfbI3fZ2b0MBYhJBjOr1WCgkNcYC4SAsgSACwh2X5hk7ePr2wCOaeYCqJDduT9CgByRP6NHWImiKclTtjvB29sXzfG-6i10fXQauWWlaqjWdt0Tvkumuvnsdj-cWrzPERz5eohmtrOuGiq-858xC4bq5zuqrb5zg6sqr35sb-P2cPZ_H52ES9uzy9n00WsOQiItVYZoSpz0LTEFMonKgsqOdDSCiEIhKYsFxkWBgOAVvMsxZSTLQjIQHrMTsa-G9f-643v5Lry2tS1akzbe5nlecoFL0OwGIPatd47Y-XGVWvlBokgd17lSu70yZ0-ufMqX73KbUB_7mf0T2uzfAf3IkPgdAy8VLUZPt1YzmcXt-EV-HjkK9-Z7Ruv3N-wfxqox5tzSYT8enH1KO_S_6zNlD4</recordid><startdate>200603</startdate><enddate>200603</enddate><creator>Cianciulli, Tomás F.</creator><creator>Lax, Jorge A.</creator><creator>Beck, Martín A.</creator><creator>Masoli, Osvaldo H.</creator><creator>Redruello, Marcela F.</creator><creator>Saccheri, María C.</creator><creator>Guevara, Eduardo</creator><creator>Gagliardi, Juan A.</creator><creator>Dorelle, Adriana N.</creator><creator>Prezioso, Horacio A.</creator><general>Blackwell Publishing Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200603</creationdate><title>Usefulness of Myocardial Contrast Echocardiography Early After Acute Myocardial Infarction</title><author>Cianciulli, Tomás F. ; Lax, Jorge A. ; Beck, Martín A. ; Masoli, Osvaldo H. ; Redruello, Marcela F. ; Saccheri, María C. ; Guevara, Eduardo ; Gagliardi, Juan A. ; Dorelle, Adriana N. ; Prezioso, Horacio A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4050-cca621a970c2d1309b29829402df555205c2675618e14051fc4631342f8202e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>acute myocardial infarction</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Albumins</topic><topic>Case-Control Studies</topic><topic>Contrast Media</topic><topic>Echocardiography</topic><topic>Female</topic><topic>Fluorocarbons</topic><topic>Humans</topic><topic>Male</topic><topic>microcirculation</topic><topic>Middle Aged</topic><topic>myocardial contrast echocardiography</topic><topic>Myocardial Infarction - diagnostic imaging</topic><topic>Myocardial Infarction - therapy</topic><topic>Myocardial Reperfusion</topic><topic>Myocardial Stunning - diagnostic imaging</topic><topic>Necrosis</topic><topic>Prospective Studies</topic><topic>reperfusion</topic><topic>stunning</topic><topic>Thrombolytic Therapy</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cianciulli, Tomás F.</creatorcontrib><creatorcontrib>Lax, Jorge A.</creatorcontrib><creatorcontrib>Beck, Martín A.</creatorcontrib><creatorcontrib>Masoli, Osvaldo H.</creatorcontrib><creatorcontrib>Redruello, Marcela F.</creatorcontrib><creatorcontrib>Saccheri, María C.</creatorcontrib><creatorcontrib>Guevara, Eduardo</creatorcontrib><creatorcontrib>Gagliardi, Juan A.</creatorcontrib><creatorcontrib>Dorelle, Adriana N.</creatorcontrib><creatorcontrib>Prezioso, Horacio A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Echocardiography (Mount Kisco, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cianciulli, Tomás F.</au><au>Lax, Jorge A.</au><au>Beck, Martín A.</au><au>Masoli, Osvaldo H.</au><au>Redruello, Marcela F.</au><au>Saccheri, María C.</au><au>Guevara, Eduardo</au><au>Gagliardi, Juan A.</au><au>Dorelle, Adriana N.</au><au>Prezioso, Horacio A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Usefulness of Myocardial Contrast Echocardiography Early After Acute Myocardial Infarction</atitle><jtitle>Echocardiography (Mount Kisco, N.Y.)</jtitle><addtitle>Echocardiography</addtitle><date>2006-03</date><risdate>2006</risdate><volume>23</volume><issue>3</issue><spage>208</spage><epage>217</epage><pages>208-217</pages><issn>0742-2822</issn><eissn>1540-8175</eissn><abstract>Objectives: (1) Evaluate wall motion and perfusion abnormalities after reperfusion therapy of the culprit lesion, (2) delineate the ability of myocardial contrast echocardiography (MCE) to evaluate the microvasculature after reperfusion, in order to distinguish between stunning and necrosis in the risk area. Methods: We analyzed 446 segments from 28 patients, 10 normal controls (160 segments), and 18 with a first AMI (286 segments). MCE was obtained with Optison and a two‐dimensional echocardiography was performed at 3 months post acute myocardial infarction (AMI). Results: In the group with AMI, we analyzed 286 segments, of which 107 had wall motion abnormalities (WMA) related to the culprit artery. Two subgroups were identified: Group I with WMA and normal perfusion (50 segments, 47%) and Group II with WMA and perfusion defects (57 segments, 53%). According to the 2D echocardiogram at 3 months, they were further subdivided into: Group IA: with wall motion improvement (stunning): 18 segments, 36%, Group IB: without wall motion improvement: 32 segments, 64%, Group IIA: with wall motion improvement: 12 segments, 21%, Group IIB: without wall motion improvement (necrosis): 45 segments, 79%. Conclusions: (1) The presence of myocardial perfusion in segments with WMA immediately after AMI reperfusion therapy predicts viability in most patients. Conversely, the lack of perfusion is not an absolute indicator of the presence of necrosis. (2) Perfusion defects allow to detect patients with thrombolysis in myocardial infarction (TIMI) 3 flow and “no‐reflow” phenomenon who will not show improved wall motion in the 2D echocardiogram. However, some patients with initial no‐reflow could have microvascular stunning and their regional contractile function will normalize after a recovery period.</abstract><cop>350 Main St , Malden , MA 02148 , USA , and PO Box 1354, Garsington Rd , Oxford OX4 2DQ , UK and PO Box 378 Carlton South , 3053 Victoria , Australia</cop><pub>Blackwell Publishing Inc</pub><pmid>16524391</pmid><doi>10.1111/j.1540-8175.2006.00190.x</doi><tpages>10</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0742-2822
ispartof Echocardiography (Mount Kisco, N.Y.), 2006-03, Vol.23 (3), p.208-217
issn 0742-2822
1540-8175
language eng
recordid cdi_proquest_miscellaneous_67734549
source Wiley-Blackwell Read & Publish Collection
subjects acute myocardial infarction
Adult
Aged
Aged, 80 and over
Albumins
Case-Control Studies
Contrast Media
Echocardiography
Female
Fluorocarbons
Humans
Male
microcirculation
Middle Aged
myocardial contrast echocardiography
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - therapy
Myocardial Reperfusion
Myocardial Stunning - diagnostic imaging
Necrosis
Prospective Studies
reperfusion
stunning
Thrombolytic Therapy
Time Factors
title Usefulness of Myocardial Contrast Echocardiography Early After Acute Myocardial Infarction
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T11%3A12%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Usefulness%20of%20Myocardial%20Contrast%20Echocardiography%20Early%20After%20Acute%20Myocardial%20Infarction&rft.jtitle=Echocardiography%20(Mount%20Kisco,%20N.Y.)&rft.au=Cianciulli,%20Tom%C3%A1s%20F.&rft.date=2006-03&rft.volume=23&rft.issue=3&rft.spage=208&rft.epage=217&rft.pages=208-217&rft.issn=0742-2822&rft.eissn=1540-8175&rft_id=info:doi/10.1111/j.1540-8175.2006.00190.x&rft_dat=%3Cproquest_cross%3E67734549%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4050-cca621a970c2d1309b29829402df555205c2675618e14051fc4631342f8202e03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=67734549&rft_id=info:pmid/16524391&rfr_iscdi=true