Effect of tension-free vaginal tape operation on urethral closure function

To evaluate whether the tension-free vaginal tape operation changes urethral hypermobility, funneling, and urethral urodynamic parameters in different parts of the urethra. We conducted a cohort study of our first 80 unselected female patients (age 36 to 78 years, median 53) undergoing a tension-fre...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2006-03, Vol.67 (3), p.524-528
Main Authors: Koelle, Dieter, Windisch, Johannes, Doerfler, Daniela, Marth, Christian, Kropshofer, Stephan
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Cohort Studies
Female
Humans
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Prostheses and Implants
Urethra - physiology
Urinary Incontinence, Stress - surgery
Urodynamics
Urologic Surgical Procedures - methods
Vagina
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Summary:To evaluate whether the tension-free vaginal tape operation changes urethral hypermobility, funneling, and urethral urodynamic parameters in different parts of the urethra. We conducted a cohort study of our first 80 unselected female patients (age 36 to 78 years, median 53) undergoing a tension-free vaginal tape procedure. Urethral pressure profile measurements were done before and 6 and 12 months after the operation. Lateral cystography was performed before and after surgery in 50 patients. Of the 80 women, 29 had previously undergone prolapse or incontinence surgery. Parameter-free techniques were used for statistical evaluation. Five patients were lost to follow-up. On an intention-to-treat basis, 66% of the patients were objectively and subjectively cured, 20% were objectively dry but subjectively occasionally incontinent, and 14% had treatment failure. The maximal urethral closure pressure at rest showed no significant changes (median baseline and 6 and 12 months postoperatively, 44, 40, and 38 cm H 2O, respectively). The pressure transmission ratio increased in the proximal urethra (median 107.5%, 122.5%, and 123.5% at baseline and 6 and 12 months postoperatively, respectively, P
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2005.09.063