Enlarged waist combined with elevated triglycerides is a strong predictor of accelerated atherogenesis and related cardiovascular mortality in postmenopausal women

Upward trends of obesity urge more effective identification of those at cardiovascular risk. A simple dichotomous indicator, enlarged waist (> or =88 cm) combined with elevated triglycerides (> or =1.45 mmol/L) (EWET), was shown to offer advantages in identifying individuals with atherogenic &...

Full description

Saved in:
Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2005-04, Vol.111 (15), p.1883-1890
Main Authors: TANKO, Laszlo B, BAGGER, Yu Z, QIN, Gerong, ALEXANDERSEN, Peter, LARSEN, Philip J, CHRISTIANSEN, Claus
Format: Article
Language:English
Subjects:
Aged
Analysis of Variance
Arteriosclerosis - diagnosis
Arteriosclerosis - epidemiology
Arteriosclerosis - etiology
Atherosclerosis (general aspects, experimental research)
Biological and medical sciences
Blood and lymphatic vessels
Body Weights and Measures - mortality
Cardiology. Vascular system
Cardiovascular Diseases - mortality
Cause of Death
Disease Progression
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Female
Humans
Hypertriglyceridemia - complications
Hypertriglyceridemia - mortality
Male
Medical sciences
Middle Aged
Neuropharmacology
Obesity - complications
Pharmacology. Drug treatments
Postmenopause
Predictive Value of Tests
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Risk Factors
Sex Factors
Waist-Hip Ratio - mortality
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Upward trends of obesity urge more effective identification of those at cardiovascular risk. A simple dichotomous indicator, enlarged waist (> or =88 cm) combined with elevated triglycerides (> or =1.45 mmol/L) (EWET), was shown to offer advantages in identifying individuals with atherogenic "lipid overaccumulation" compared with other indicators, including the metabolic syndrome defined by the National Cholesterol Education Program (MS-NCEP). Whether EWET offers superior disease and event prediction in postmenopausal women, however, remains unknown. A community-based sample of 557 women (48 to 76 years of age) were followed up for 8.5+/-0.3 years to assess the utility of EWET and MS-NCEP in estimating the risk of all-cause and cardiovascular mortality and the annual progression rate of aortic calcification. At baseline, 15.8% of women had EWET and 17.6% had MS-NCEP. All-cause mortality and cardiovascular mortality were increased in carriers of the dichotomous indicators (P
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.0000161801.65408.8D