Carbohydrate-coated nanocapsules from amphiphilic rod-coil molecule: binding to bacterial type 1 pili

Stable carbohydrate-coated nanocapsules designed as multivalent nanoscaffolds for selective interactions with receptors are able to encapsulate guest molecules within their interior and to bind efficiently to FimH adhesin of bacterial type 1 pili.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2005-04 (15), p.2035-2037
Main Authors: Kim, Byung-Sun, Yang, Won-Young, Ryu, Ja-Hyoung, Yoo, Yong-Sik, Lee, Myongsoo
Format: Article
Language:English
Subjects:
Carbohydrates - chemistry
Escherichia coli - chemistry
Escherichia coli - ultrastructure
Fimbriae, Bacterial - chemistry
Fimbriae, Bacterial - ultrastructure
Microscopy, Electron, Scanning
Microscopy, Electron, Transmission
Molecular Structure
Nanocapsules - chemistry
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Description
Summary:Stable carbohydrate-coated nanocapsules designed as multivalent nanoscaffolds for selective interactions with receptors are able to encapsulate guest molecules within their interior and to bind efficiently to FimH adhesin of bacterial type 1 pili.
ISSN:1359-7345
1364-548X
DOI:10.1039/b419258c