Sentinel node biopsy is not sensible in breast cancer patients with large primary tumours

We aimed to evaluate the outcome of sentinel node biopsy (SNB) in breast cancer patients with large primary tumours. Nine hundred and eighty-four patients with invasive breast cancer and SNB were studied. The histological tumour size was larger than 3 cm in 70 patients. The advantages of SNB like av...

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Bibliographic Details
Published in:European journal of surgical oncology 2005-05, Vol.31 (4), p.364-368
Main Authors: Leidenius, M H K, Krogerus, L A, Toivonen, T S, von Smitten, K A J
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Axilla
Breast Neoplasms - pathology
Chi-Square Distribution
Female
Humans
Lymphatic Metastasis
Middle Aged
Neoplasm Invasiveness
Neoplasm Staging
Sentinel Lymph Node Biopsy - utilization
Statistics, Nonparametric
Sternum
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Summary:We aimed to evaluate the outcome of sentinel node biopsy (SNB) in breast cancer patients with large primary tumours. Nine hundred and eighty-four patients with invasive breast cancer and SNB were studied. The histological tumour size was larger than 3 cm in 70 patients. The advantages of SNB like avoiding axillary clearance (AC) or more accurate staging by detecting micrometastases or parasternal sentinel node metastases were evaluated in relation to the tumour size. Axillary metastases were detected in 351/914 patients with a tumour size of 3 cm or smaller and in 50/70 patients with larger tumours (p
ISSN:0748-7983
DOI:10.1016/j.ejso.2004.11.006