A case of idiopathic sclerosing mediastinitis in a 7-year-old Japanese boy

Sclerosing mediastinitis is a very rare benign disorder characterised by the development of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon especially in areas without endemic histoplasmosis. We report a Japanese boy with mar...

Full description

Saved in:
Bibliographic Details
Published in:European journal of pediatrics 2005-05, Vol.164 (5), p.302-305
Main Authors: SHINKAWA, Tomoko, NAKAJIMA, Mitsuru, KISHIMOTO, Tomoko, INAGAKI, Jiro, PARK, Young-Dong, KUSHIBE, Keiji, TANIGUCHI, Shigeki, NAKAGAWA, Atsuko, YOSHIOKA, Akira
Format: Article
Language:English
Subjects:
Anemia - etiology
Asian Continental Ancestry Group
Biological and medical sciences
Biomarkers - blood
Blood Sedimentation
C-Reactive Protein - analysis
Child
General aspects
Humans
Immunoglobulin G - blood
Japan
Male
Mediastinitis - diagnosis
Mediastinitis - surgery
Mediastinum - diagnostic imaging
Mediastinum - pathology
Mediastinum - surgery
Medical sciences
Radionuclide Imaging
Sclerosis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sclerosing mediastinitis is a very rare benign disorder characterised by the development of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon especially in areas without endemic histoplasmosis. We report a Japanese boy with markedly elevated serum inflammatory markers for more than 1 year in the absence of any clinical manifestations. 67Ga-scintigraphy demonstrated an accumulation in the mediastinal region and an open biopsy revealed a hard fibrous mass in the anteriosuperior mediastinum. Thus, a diagnosis of idiopathic sclerosing mediastinitis was made. To the best of our knowledge, this case is the youngest patient reported with this disorder. In patients with mediastinal mass lesions the diagnosis of sclerosing mediastinitis should be considered as well as infectious, autoimmune or neoplastic disease even in children.
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-005-1644-9