Predicting final infarct size using acute and subacute multiparametric MRI measurements in patients with ischemic stroke

Purpose To identify early MRI characteristics of ischemic stroke that predict final infarct size three months poststroke. Materials and Methods Multiparametric MRI (multispin echo T2‐weighted [T2W] imaging, T1‐weighted [T1W] imaging, and diffusion‐weighted imaging [DWI]) was performed acutely ( acut...

Full description

Saved in:
Bibliographic Details
Published in:Journal of magnetic resonance imaging 2005-05, Vol.21 (5), p.495-502
Main Authors: Lu, Mei, Mitsias, Panayiotis D., Ewing, James R., Soltanian-Zadeh, Hamid, Bagher-Ebadian, Hassan, Zhao, Qingming, Oja-Tebbe, Nancy, Patel, Suresh C., Chopp, Michael
Format: Article
Language:English
Subjects:
Acute Disease
Brain Ischemia - pathology
Cerebral Infarction - pathology
Female
generalized estimating equations (GEE)
Humans
Image Processing, Computer-Assisted
ischemic stroke
magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
prediction
Predictive Value of Tests
thrombolysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To identify early MRI characteristics of ischemic stroke that predict final infarct size three months poststroke. Materials and Methods Multiparametric MRI (multispin echo T2‐weighted [T2W] imaging, T1‐weighted [T1W] imaging, and diffusion‐weighted imaging [DWI]) was performed acutely ( acute DWI lesion size predicted an increased final infarct size (P < 0.01). Conclusion Acute‐phase DWI and DWI‐ISODATA mismatch strongly predict the final infarct size. An acute‐to‐subacute DWI lesion size change further increases the predictive ability of the model. J. Magn. Reson. Imaging 2005;21:495–502. © 2005 Wiley‐Liss, Inc.
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.20313