Long-Term Results of Renal Transplantation: A Single-Center Analysis of 1200 Transplants

The present study is a report of long-term results of the first 1200 operations from December 1988 to December 2003. Graft and patient survival rates in eligible cases were computed with Kaplan-Meier analysis. Recipients were 808 men, 392 women of mean age 33.6 ± 12.5 years. Eighty six percent of ca...

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Bibliographic Details
Published in:Transplantation proceedings 2006-03, Vol.38 (2), p.454-456
Main Authors: Malek-Hosseini, S., Razmkon, A., Mehdizadeh, A., Salahi, H., Bahador, A., Raiss-Jalali, G.H., Roozbeh, J., Behzadi, S., Salehipour, M., Khosravi, M., Anbardar, M.H.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biological and medical sciences
Cadaver
Child
Child, Preschool
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Graft Rejection - epidemiology
Humans
Kidney Failure, Chronic - classification
Kidney Failure, Chronic - surgery
Kidney Transplantation - immunology
Kidney Transplantation - mortality
Kidney Transplantation - physiology
Length of Stay
Living Donors
Male
Medical sciences
Middle Aged
Retrospective Studies
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Survival Analysis
Time Factors
Tissue Donors
Tissue, organ and graft immunology
Treatment Outcome
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Summary:The present study is a report of long-term results of the first 1200 operations from December 1988 to December 2003. Graft and patient survival rates in eligible cases were computed with Kaplan-Meier analysis. Recipients were 808 men, 392 women of mean age 33.6 ± 12.5 years. Eighty six percent of cases used organs from living donors (40% related, 41% unrelated, and 5% spouses) and 14% from cadaveric source. The most common causes of end-stage renal disease were chronic glomerulonephritis (18.2%); reflux nephropathy (13.4%); and diabetic nephropathy (10.1%). Among 215 (17.9%) patients, 156 patients (13%) died in the posttransplant period. Most common causes of death were cardiovascular (28.3%), graft loss (20.7%), and infections (19.6%). The 1- and 3-year patient survival rates were 94% and 91.5%, and graft survival rates were 88% and 84%. Although the success rate of operations was not satisfactory at the beginning, the current data reflect a >90% survival rate comparable to the major centers in the world.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2006.01.020