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Does Earlier Headache Response Equate to Earlier Return to Functioning in Patients Suffering from Migraine?
This study explored the association between headache response and return to functioning, and identified migraine-associated symptoms related to functional status and acceptability of migraine treatment as reported by patients. Data from migraineurs enrolled in the active arms of a randomized, double...
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| Published in: | Cephalalgia 2006-04, Vol.26 (4), p.428-435 |
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| Main Authors: | , , , , |
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| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c4453-a8d4b01f42dc769119e727d5a1e39bfe6d2c9aac1b8c1fe0ad2b5a6df63c6f473 |
| container_end_page | 435 |
| container_issue | 4 |
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| container_title | Cephalalgia |
| container_volume | 26 |
| creator | Pradel, FG Subedi, P Varghese, AA Mullins, CD Weis, KA |
| description | This study explored the association between headache response and return to functioning, and identified migraine-associated symptoms related to functional status and acceptability of migraine treatment as reported by patients. Data from migraineurs enrolled in the active arms of a randomized, double-blind, parallel group, placebo-controlled, clinical trial were analysed. The relationships between headache response and functional response, and clinical factors and treatment acceptability were assessed using X
2 tests of proportions and logistic regressions. A greater proportion of patients with headache response at 0.5 h were functioning at 0.5, 1 and 2 h compared with patients who did not attain a headache response at 0.5 h (P < 0.0001). These patients also were more likely to find their treatment acceptable (P < 0.05). The results suggest a direct temporal relationship among the key determinants of migraine resolution. Rapid headache response is associated with faster return to functioning; rapid headache and functional responses are significant attributes of treatment acceptability. |
| doi_str_mv | 10.1111/j.1468-2982.2005.01043.x |
| format | article |
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2 tests of proportions and logistic regressions. A greater proportion of patients with headache response at 0.5 h were functioning at 0.5, 1 and 2 h compared with patients who did not attain a headache response at 0.5 h (P < 0.0001). These patients also were more likely to find their treatment acceptable (P < 0.05). The results suggest a direct temporal relationship among the key determinants of migraine resolution. Rapid headache response is associated with faster return to functioning; rapid headache and functional responses are significant attributes of treatment acceptability.</description><identifier>ISSN: 0333-1024</identifier><identifier>EISSN: 1468-2982</identifier><identifier>DOI: 10.1111/j.1468-2982.2005.01043.x</identifier><identifier>PMID: 16556244</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Comorbidity ; Double-Blind Method ; Female ; functioning ; headache ; Headache - drug therapy ; Headache - epidemiology ; Humans ; Incidence ; Male ; Maryland - epidemiology ; Middle Aged ; Migraine ; Migraine Disorders - drug therapy ; Migraine Disorders - epidemiology ; Outcome Assessment (Health Care) - methods ; Patient Satisfaction - statistics & numerical data ; Pyrrolidines - therapeutic use ; Recovery of Function ; satisfaction ; Serotonin Receptor Agonists - therapeutic use ; Sumatriptan - therapeutic use ; Treatment Outcome ; Tryptamines - therapeutic use</subject><ispartof>Cephalalgia, 2006-04, Vol.26 (4), p.428-435</ispartof><rights>2006 International Headache Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4453-a8d4b01f42dc769119e727d5a1e39bfe6d2c9aac1b8c1fe0ad2b5a6df63c6f473</citedby><cites>FETCH-LOGICAL-c4453-a8d4b01f42dc769119e727d5a1e39bfe6d2c9aac1b8c1fe0ad2b5a6df63c6f473</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1111/j.1468-2982.2005.01043.x$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1111/j.1468-2982.2005.01043.x$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21966,27853,27924,27925,44945,45333</link.rule.ids><linktorsrc>$$Uhttps://journals.sagepub.com/doi/full/10.1111/j.1468-2982.2005.01043.x?utm_source=summon&utm_medium=discovery-provider$$EView_record_in_SAGE_Publications$$FView_record_in_$$GSAGE_Publications</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16556244$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pradel, FG</creatorcontrib><creatorcontrib>Subedi, P</creatorcontrib><creatorcontrib>Varghese, AA</creatorcontrib><creatorcontrib>Mullins, CD</creatorcontrib><creatorcontrib>Weis, KA</creatorcontrib><title>Does Earlier Headache Response Equate to Earlier Return to Functioning in Patients Suffering from Migraine?</title><title>Cephalalgia</title><addtitle>Cephalalgia</addtitle><description>This study explored the association between headache response and return to functioning, and identified migraine-associated symptoms related to functional status and acceptability of migraine treatment as reported by patients. Data from migraineurs enrolled in the active arms of a randomized, double-blind, parallel group, placebo-controlled, clinical trial were analysed. The relationships between headache response and functional response, and clinical factors and treatment acceptability were assessed using X
2 tests of proportions and logistic regressions. A greater proportion of patients with headache response at 0.5 h were functioning at 0.5, 1 and 2 h compared with patients who did not attain a headache response at 0.5 h (P < 0.0001). These patients also were more likely to find their treatment acceptable (P < 0.05). The results suggest a direct temporal relationship among the key determinants of migraine resolution. Rapid headache response is associated with faster return to functioning; rapid headache and functional responses are significant attributes of treatment acceptability.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Comorbidity</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>functioning</subject><subject>headache</subject><subject>Headache - drug therapy</subject><subject>Headache - epidemiology</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Maryland - epidemiology</subject><subject>Middle Aged</subject><subject>Migraine</subject><subject>Migraine Disorders - drug therapy</subject><subject>Migraine Disorders - epidemiology</subject><subject>Outcome Assessment (Health Care) - methods</subject><subject>Patient Satisfaction - statistics & numerical data</subject><subject>Pyrrolidines - therapeutic use</subject><subject>Recovery of Function</subject><subject>satisfaction</subject><subject>Serotonin Receptor Agonists - therapeutic use</subject><subject>Sumatriptan - therapeutic use</subject><subject>Treatment Outcome</subject><subject>Tryptamines - therapeutic use</subject><issn>0333-1024</issn><issn>1468-2982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNqNkU9P3DAQxS1UBAvtV6h86i2p_8VJLlTVdukigUDQni3HGW-9ZO3FTlT49iTsCo7gy1gzv3m23kMIU5LT8Xxf51TIKmN1xXJGSJETSgTPHw_Q7HXwCc0I5zyjhIljdJLSmoykJPIIHVNZFJIJMUP3vwIkvNCxcxDxEnSrzT_At5C2wSfAi4dB94D78MrcQj9EP3XOB296F7zzK-w8vtG9A98nfDdYC3Hq2hg2-MqtonYefnxGh1Z3Cb7s6yn6e774M19ml9e_L-Y_LzMjRMEzXbWiIdQK1ppS1pTWULKyLTQFXjcWZMtMrbWhTWWoBaJb1hRatlZyI60o-Sn6ttPdxvAwQOrVxiUDXac9hCEpWZZlTTh7F2SU8FqwSbHagSaGlCJYtY1uo-OTokRNiai1moxXk_FqSkS9JKIex9Wv-zeGZgPt2-I-ghE42wH_XQdPHxZW88XNcrqOAsVOIOkVqHUY0xndff9nz3NPqwY</recordid><startdate>200604</startdate><enddate>200604</enddate><creator>Pradel, FG</creator><creator>Subedi, P</creator><creator>Varghese, AA</creator><creator>Mullins, CD</creator><creator>Weis, KA</creator><general>SAGE Publications</general><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>200604</creationdate><title>Does Earlier Headache Response Equate to Earlier Return to Functioning in Patients Suffering from Migraine?</title><author>Pradel, FG ; Subedi, P ; Varghese, AA ; Mullins, CD ; Weis, KA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4453-a8d4b01f42dc769119e727d5a1e39bfe6d2c9aac1b8c1fe0ad2b5a6df63c6f473</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Comorbidity</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>functioning</topic><topic>headache</topic><topic>Headache - drug therapy</topic><topic>Headache - epidemiology</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Maryland - epidemiology</topic><topic>Middle Aged</topic><topic>Migraine</topic><topic>Migraine Disorders - drug therapy</topic><topic>Migraine Disorders - epidemiology</topic><topic>Outcome Assessment (Health Care) - methods</topic><topic>Patient Satisfaction - statistics & numerical data</topic><topic>Pyrrolidines - therapeutic use</topic><topic>Recovery of Function</topic><topic>satisfaction</topic><topic>Serotonin Receptor Agonists - therapeutic use</topic><topic>Sumatriptan - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Tryptamines - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pradel, FG</creatorcontrib><creatorcontrib>Subedi, P</creatorcontrib><creatorcontrib>Varghese, AA</creatorcontrib><creatorcontrib>Mullins, CD</creatorcontrib><creatorcontrib>Weis, KA</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Cephalalgia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Pradel, FG</au><au>Subedi, P</au><au>Varghese, AA</au><au>Mullins, CD</au><au>Weis, KA</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does Earlier Headache Response Equate to Earlier Return to Functioning in Patients Suffering from Migraine?</atitle><jtitle>Cephalalgia</jtitle><addtitle>Cephalalgia</addtitle><date>2006-04</date><risdate>2006</risdate><volume>26</volume><issue>4</issue><spage>428</spage><epage>435</epage><pages>428-435</pages><issn>0333-1024</issn><eissn>1468-2982</eissn><abstract>This study explored the association between headache response and return to functioning, and identified migraine-associated symptoms related to functional status and acceptability of migraine treatment as reported by patients. Data from migraineurs enrolled in the active arms of a randomized, double-blind, parallel group, placebo-controlled, clinical trial were analysed. The relationships between headache response and functional response, and clinical factors and treatment acceptability were assessed using X
2 tests of proportions and logistic regressions. A greater proportion of patients with headache response at 0.5 h were functioning at 0.5, 1 and 2 h compared with patients who did not attain a headache response at 0.5 h (P < 0.0001). These patients also were more likely to find their treatment acceptable (P < 0.05). The results suggest a direct temporal relationship among the key determinants of migraine resolution. Rapid headache response is associated with faster return to functioning; rapid headache and functional responses are significant attributes of treatment acceptability.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>16556244</pmid><doi>10.1111/j.1468-2982.2005.01043.x</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 0333-1024 |
| ispartof | Cephalalgia, 2006-04, Vol.26 (4), p.428-435 |
| issn | 0333-1024 1468-2982 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67779032 |
| source | SAGE Open Access Journals |
| subjects | Adolescent Adult Aged Aged, 80 and over Comorbidity Double-Blind Method Female functioning headache Headache - drug therapy Headache - epidemiology Humans Incidence Male Maryland - epidemiology Middle Aged Migraine Migraine Disorders - drug therapy Migraine Disorders - epidemiology Outcome Assessment (Health Care) - methods Patient Satisfaction - statistics & numerical data Pyrrolidines - therapeutic use Recovery of Function satisfaction Serotonin Receptor Agonists - therapeutic use Sumatriptan - therapeutic use Treatment Outcome Tryptamines - therapeutic use |
| title | Does Earlier Headache Response Equate to Earlier Return to Functioning in Patients Suffering from Migraine? |
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