Eosinophilic esophagitis is frequently associated with IgE-mediated allergic airway diseases

In patients with EE with concomitant allergic rhinitis, the age of onset of allergic rhinitis (median, 6 years; range, 2-27 years) was significantly earlier than that of dysphagia (median, 22 years; range, 7-39 years; P < .001; Fig 1). [...]it appears that EE is just an additional involvement of...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2005-05, Vol.115 (5), p.1090-1092
Main Authors: Simon, Dagmar, Marti, Hanspeter, Heer, Pius, Simon, Hans-Uwe, Braathen, Lasse R., Straumann, Alex
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Allergens - adverse effects
Allergens - immunology
Allergies
Antibody Specificity
Asthma
Dysphagia
Eosinophilia - pathology
Esophagitis - etiology
Esophagitis - pathology
Female
Food
Food - adverse effects
Humans
Immunoglobulin E - blood
Male
Middle Aged
Milk
Patients
Pollen
Prospective Studies
Respiratory Hypersensitivity - blood
Respiratory Hypersensitivity - complications
Respiratory Hypersensitivity - etiology
Studies
Citations: Items that cite this one
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Summary:In patients with EE with concomitant allergic rhinitis, the age of onset of allergic rhinitis (median, 6 years; range, 2-27 years) was significantly earlier than that of dysphagia (median, 22 years; range, 7-39 years; P < .001; Fig 1). [...]it appears that EE is just an additional involvement of another organ, the esophagus, in a preexisting IgE-mediated allergic syndrome. Because the relevant allergens do not change in this process, it is possible that factors unrelated to atopy determine the susceptibility for the development of EE in patients with allergic rhinitis with or without bronchial asthma.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2005.01.017