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Biosensors for real-time in vivo measurements

The current status of sensors capable of continuous measurement of analytes in biological media is reviewed. This review containing 173 references deals with devices whose use in single cells, tissue slices, animal models and humans has been demonstrated. In addition to sensors specific for glucose,...

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Published in:	Biosensors & bioelectronics 2005-06, Vol.20 (12), p.2388-2403
Main Authors:	Wilson, George S., Gifford, Raeann
Format:	Article
Language:	English
Subjects:	Biocompatibility Biological and medical sciences Biosensing Techniques - instrumentation Biosensing Techniques - methods Biosensing Techniques - trends Biosensor Biosensors Biotechnology Blood Glucose - analysis Blood Glucose Self-Monitoring - instrumentation Blood Glucose Self-Monitoring - methods Cell Culture Techniques - instrumentation Cell Culture Techniques - methods Continuous monitoring of glucose Equipment Design Fundamental and applied biological sciences. Psychology Methods. Procedures. Technologies Monitoring, Ambulatory - instrumentation Monitoring, Ambulatory - methods Prostheses and Implants Transducers Various methods and equipments
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description	The current status of sensors capable of continuous measurement of analytes in biological media is reviewed. This review containing 173 references deals with devices whose use in single cells, tissue slices, animal models and humans has been demonstrated. In addition to sensors specific for glucose, lactate, glutamate, pyruvate, choline and acetylcholine, insights obtained from monitoring nitric oxide, Na +, K +, Ca 2+, and dopamine are presented. Performance criteria for sensor performance are described as is the subject of biosensor calibration. Biocompatibility issues are dealt with in some detail as is the status of continuous blood glucose monitoring in humans.
doi_str_mv	10.1016/j.bios.2004.12.003
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subjects	Biocompatibility Biological and medical sciences Biosensing Techniques - instrumentation Biosensing Techniques - methods Biosensing Techniques - trends Biosensor Biosensors Biotechnology Blood Glucose - analysis Blood Glucose Self-Monitoring - instrumentation Blood Glucose Self-Monitoring - methods Cell Culture Techniques - instrumentation Cell Culture Techniques - methods Continuous monitoring of glucose Equipment Design Fundamental and applied biological sciences. Psychology Methods. Procedures. Technologies Monitoring, Ambulatory - instrumentation Monitoring, Ambulatory - methods Prostheses and Implants Transducers Various methods and equipments
title	Biosensors for real-time in vivo measurements
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