Simultaneous occurrence of pure red cell aplasia and papular‐purpuric ‘gloves and socks’ syndrome in parvovirus B‐19 infection

ABSTRACT Papular‐purpuric ‘gloves and socks’ syndrome (PPGSS) has been associated with parvovirus B‐19 infection. We report a case of an adult immunocompetent male who presented with PPGSS. Bone marrow examination revealed pure red cell aplasia. Parvovirus B‐19 DNA was detected by polymerase chain r...

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Bibliographic Details
Published in:Journal of the European Academy of Dermatology and Venereology 2005-05, Vol.19 (3), p.373-376
Main Authors: Loukeris, D, Serelis, J, Aroni, K, Tsakris, A, Voulgarelis, M
Format: Article
Language:English
Subjects:
Adult
Foot Dermatoses - etiology
Hand Dermatoses - etiology
Humans
Male
papular‐purpuric ‘gloves and socks’ syndrome
Parvoviridae Infections - complications
Parvovirus B19, Human
parvovirus B‐19
pure red cell aplasia
Red-Cell Aplasia, Pure - etiology
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Summary:ABSTRACT Papular‐purpuric ‘gloves and socks’ syndrome (PPGSS) has been associated with parvovirus B‐19 infection. We report a case of an adult immunocompetent male who presented with PPGSS. Bone marrow examination revealed pure red cell aplasia. Parvovirus B‐19 DNA was detected by polymerase chain reaction in the patient's serum, whole blood and in the cutaneous lesions. This report illustrates the variety of clinical manifestations caused by B‐19 infection, presents for the first time the concurrent appearance of pure red cell aplasia and PPGSS in the same patient and, finally, suggests that PPGSS may be due to direct lytic effect of the virus.
ISSN:0926-9959
1468-3083
DOI:10.1111/j.1468-3083.2004.01172.x