Myofibrosarcoma of the adrenal gland

Adrenal masses have varying presentations. Most commonly, adrenal masses are discovered incidentally on CT or MRI during an evaluation for an unrelated complaint. Although the majority of these are nonfunctional cortical adenomas, hormonally active tumors and adrenocortical carcinoma must also be co...

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Bibliographic Details
Published in:The American surgeon 2005-03, Vol.71 (3), p.191-193
Main Authors: McLaughlin, S A, Schmitt, T M, Huguet, K L, Menke, D M, Nguyen, J H
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - pathology
Adrenal Gland Neoplasms - surgery
Adrenal glands
Adrenalectomy - methods
Biopsy, Needle
Follow-Up Studies
Humans
Immunohistochemistry
Male
Medical diagnosis
Middle Aged
Myosarcoma - pathology
Myosarcoma - surgery
Neoplasm Staging
Pathology
Risk Assessment
Surgery
Tomography, X-Ray Computed
Tumors
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Summary:Adrenal masses have varying presentations. Most commonly, adrenal masses are discovered incidentally on CT or MRI during an evaluation for an unrelated complaint. Although the majority of these are nonfunctional cortical adenomas, hormonally active tumors and adrenocortical carcinoma must also be considered in the differential diagnosis. Rarely, retroperitoneal tumors may mimic an adrenal mass. We report a case of a 49-year-old man with anemia and weight loss who was found to have a large retroperitoneal mass arising from the adrenal gland. Surgical treatment involved en bloc resection of the right kidney, adrenal gland, segments 7 and 8 of the liver, and a portion of the right hemidiaphragm. Final pathology revealed a low-grade myofibrosarcoma. We believe that this is the first case report of a myofibrosarcoma of the adrenal gland. Myofibrosarcomas are rare malignant tumors composed of myofibroblasts that arise from the deep soft tissues. These tumors have a predilection for the head and neck, trunk, or extremities. Myofibrosarcomas can be differentiated from other sarcomas by immunohistochemical staining and pathologic features. We will briefly discuss the workup of an adrenal mass and focus on the diagnosis of myofibrosarcoma.
ISSN:0003-1348
1555-9823
DOI:10.1177/000313480507100302