Skin-prick testing as a diagnostic aid for childhood asthma

Diagnosing asthma is problematic when based solely on reported symptoms. The purpose of this study was to evaluate skin‐prick testing as a diagnostic aid for asthma in children. Skin‐prick testing (SPT) was undertaken in children aged 2–10 years with either no history of wheeze (n = 149) or recent d...

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Published in:Pediatric pulmonology 2005-06, Vol.39 (6), p.558-562
Main Authors: Chan, E.Y., Dundas, I., Bridge, P.D., Healy, M.J.R., McKenzie, S.A.
Format: Article
Language:English
Subjects:
Age Factors
Asthma - diagnosis
atopy
Biological and medical sciences
Child
Child, Preschool
children
Chronic obstructive pulmonary disease, asthma
diagnosis of asthma
Female
Humans
Male
Medical sciences
Pneumology
Predictive Value of Tests
skin prick test
Skin Tests
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cited_by cdi_FETCH-LOGICAL-c3957-5f90cc541219200890035ac25396e9639a1edaabb594c004745be902388967f53
cites cdi_FETCH-LOGICAL-c3957-5f90cc541219200890035ac25396e9639a1edaabb594c004745be902388967f53
container_end_page 562
container_issue 6
container_start_page 558
container_title Pediatric pulmonology
container_volume 39
creator Chan, E.Y.
Dundas, I.
Bridge, P.D.
Healy, M.J.R.
McKenzie, S.A.
description Diagnosing asthma is problematic when based solely on reported symptoms. The purpose of this study was to evaluate skin‐prick testing as a diagnostic aid for asthma in children. Skin‐prick testing (SPT) was undertaken in children aged 2–10 years with either no history of wheeze (n = 149) or recent doctor‐observed wheeze which responded to treatment with a bronchodilator, the “gold standard” (n = 164). Children with moderate or severe asthma were excluded. SPT positivity increased sharply at age 5 years in wheezers. Data were therefore divided into two age groups: 2–
doi_str_mv 10.1002/ppul.20227
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The purpose of this study was to evaluate skin‐prick testing as a diagnostic aid for asthma in children. Skin‐prick testing (SPT) was undertaken in children aged 2–10 years with either no history of wheeze (n = 149) or recent doctor‐observed wheeze which responded to treatment with a bronchodilator, the “gold standard” (n = 164). Children with moderate or severe asthma were excluded. SPT positivity increased sharply at age 5 years in wheezers. Data were therefore divided into two age groups: 2–&lt;5 years (57 controls, 97 wheezers) and 5–10 years (92 controls, 67 wheezers). The sensitivity, specificity, and likelihood ratios of SPT positivity for wheeze were 32%, 89%, and 2.9, respectively, in the younger children, and 82%, 85%, and 5.5, respectively, in the older children. For a prevalence of 30% for asthma, the positive predictive values of a positive SPT were 55% and 70% for the younger and older age groups, respectively. The test characteristics of SPT for helping diagnose asthma in schoolchildren are good. The prevalence of wheeze in preschool children is high, and so SPT should be helpful even in this group. 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Pulmonol</addtitle><description>Diagnosing asthma is problematic when based solely on reported symptoms. The purpose of this study was to evaluate skin‐prick testing as a diagnostic aid for asthma in children. Skin‐prick testing (SPT) was undertaken in children aged 2–10 years with either no history of wheeze (n = 149) or recent doctor‐observed wheeze which responded to treatment with a bronchodilator, the “gold standard” (n = 164). Children with moderate or severe asthma were excluded. SPT positivity increased sharply at age 5 years in wheezers. Data were therefore divided into two age groups: 2–&lt;5 years (57 controls, 97 wheezers) and 5–10 years (92 controls, 67 wheezers). The sensitivity, specificity, and likelihood ratios of SPT positivity for wheeze were 32%, 89%, and 2.9, respectively, in the younger children, and 82%, 85%, and 5.5, respectively, in the older children. 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source Wiley-Blackwell Read & Publish Collection
subjects Age Factors
Asthma - diagnosis
atopy
Biological and medical sciences
Child
Child, Preschool
children
Chronic obstructive pulmonary disease, asthma
diagnosis of asthma
Female
Humans
Male
Medical sciences
Pneumology
Predictive Value of Tests
skin prick test
Skin Tests
title Skin-prick testing as a diagnostic aid for childhood asthma
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