Hes1 Directly Controls Cell Proliferation through the Transcriptional Repression of p27Kip1

• Published in: Molecular and Cellular Biology 2005-05, Vol.25 (10), p.4262-4271
• Main Authors: Murata, Kaoru, Hattori, Masakazu, Hirai, Norihito, Shinozuka, Yoriko, Hirata, Hiromi, Kageyama, Ryoichiro, Sakai, Toshiyuki, Minato, Nagahiro
• Format: Article
• Language: English
• Subjects: 5' Flanking Region - genetics; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Count; Cell Cycle Proteins - biosynthesis; Cell Cycle Proteins - genetics; Cell Cycle Proteins - metabolism; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation - drug effects; Embryo, Mammalian - cytology; Embryo, Mammalian - metabolism; HeLa Cells; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; Humans; Mice; Promoter Regions, Genetic - genetics; Proteasome Endopeptidase Complex - metabolism; Protein Processing, Post-Translational; Repressor Proteins - genetics; Repressor Proteins - metabolism; Signal Transduction; Transcription Factor HES-1; Transcription, Genetic - genetics; Tretinoin - pharmacology; Tumor Suppressor Proteins - biosynthesis; Tumor Suppressor Proteins - genetics; Tumor Suppressor Proteins - metabolism
• ISSN: 0270-7306; 1098-5549
• DOI: 10.1128/MCB.25.10.4262-4271.2005

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