Effect of iron supplementation on mental and motor development in children: systematic review of randomised controlled trials

To evaluate the effect of iron supplementation on mental and motor development in children through a systematic review of randomised controlled trials (RCTs). Electronic databases, personal files, hand search of reviews, bibliographies of books, abstracts and proceedings of international conferences...

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Bibliographic Details
Published in:Public health nutrition 2005-04, Vol.8 (2), p.117-132
Main Authors: Sachdev, HPS, Gera, Tarun, Nestel, Penelope
Format: Article
Language:English
Subjects:
Adolescent
Age
Anaemia
Anemia
anemia (disease)
Anemia, Iron-Deficiency - complications
Anemia, Iron-Deficiency - drug therapy
Bibliographic literature
Cereals
Child
Child Development - drug effects
child nutrition
Child, Preschool
clinical trials
Cognition
Cognition & reasoning
Cognition - drug effects
cognitive development
deficiency
dietary mineral supplements
Dietary Supplements
Female
Heterogeneity
Humans
Infant
infant nutrition
Infant, Newborn
infants
Intelligence tests
International conferences
Intervention
Iron
Iron - administration & dosage
Iron - therapeutic use
iron deficiency anemia
Iron supplementation
literature reviews
Male
Mental development
Meta-analysis
Motor development
preschool children
psychomotor development
Psychomotor Performance - drug effects
Randomised controlled trials
Randomized Controlled Trials as Topic
school children
Systematic review
Time Factors
Treatment Outcome
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Summary:To evaluate the effect of iron supplementation on mental and motor development in children through a systematic review of randomised controlled trials (RCTs). Electronic databases, personal files, hand search of reviews, bibliographies of books, abstracts and proceedings of international conferences. RCTs with interventions that included oral or parenteral iron supplementation, fortified formula milk or cereals were evaluated. The outcomes studied were mental and motor development scores and various individual development tests employed, including Bayley mental and psychomotor development indices and intelligence quotient. The pooled estimate (random effects model) of mental development score standardised mean difference (SMD) was 0.30 (95% confidence interval (CI) 0.15 to 0.46, P
ISSN:1368-9800
1475-2727
DOI:10.1079/PHN2004677