Effects of an ad libitum low-glycemic load diet on cardiovascular disease risk factors in obese young adults

Background: The optimal nutritional approach for the prevention of cardiovascular disease among obese persons remains a topic of intense controversy. Available approaches range from conventional low-fat to very-low-carbohydrate diets. Objective: The aim of this pilot study was to evaluate the effica...

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Bibliographic Details
Published in:The American journal of clinical nutrition 2005-05, Vol.81 (5), p.976-982
Main Authors: Ebbeling, C.B, Leidig, M.M, Sinclair, K.B, Seger-Shippee, L.G, Feldman, H.A, Ludwig, D.S
Format: Article
Language:English
Subjects:
ad libitum feeding
Adult
Biological and medical sciences
Blood Pressure
Cardiovascular disease
cardiovascular diseases
Cardiovascular Diseases - etiology
Cholesterol - blood
Diet
Dietary Carbohydrates - administration & dosage
Dietary Fats - administration & dosage
Exercise
Feeding. Feeding behavior
Female
food composition
Fundamental and applied biological sciences. Psychology
glycemic control
glycemic effect
Glycemic Index
glycemic load
Humans
long term effects
Male
nutritional intervention
Obesity
Obesity - blood
Obesity - complications
Obesity - diet therapy
obesity-related diseases
plasminogen activator
proteinase inhibitors
Risk Factors
risk reduction
Vertebrates: anatomy and physiology, studies on body, several organs or systems
weight control programs
weight reducing diet
Young adults
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Summary:Background: The optimal nutritional approach for the prevention of cardiovascular disease among obese persons remains a topic of intense controversy. Available approaches range from conventional low-fat to very-low-carbohydrate diets. Objective: The aim of this pilot study was to evaluate the efficacy of an ad libitum low-glycemic load diet, without strict limitation on carbohydrate intake, as an alternative to a conventional low-fat diet. Design: A randomized controlled trial compared 2 dietary treatments in obese young adults (n = 23) over 12 mo. The experimental treatment emphasized ad libitum consumption of low-glycemic-index foods, with 45-50% of energy from carbohydrates and 30-35% from fat. The conventional treatment was restricted in energy (250-500 kcal/d deficit) and fat (
ISSN:0002-9165
1938-3207
DOI:10.1093/ajcn/81.5.976