Intracranial aneurysms treated with guglielmi detachable coils : Imaging follow-up with contrast-enhanced MR angiography

• Published in: Stroke (1970) 2006-04, Vol.37 (4), p.1033-1037
• Main Authors: GAUVRIT, Jean-Yves, LECLERC, Xavier, CARON, Sabine, TASCHNER, Christian A, LEJEUNE, Jean-Paul, PRUVO, Jean-Pierre
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Angiography, Digital Subtraction - standards; Biological and medical sciences; Contrast Media; Diseases of the nervous system; Embolization, Therapeutic - instrumentation; Equipment Design; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Intracranial Aneurysm - diagnosis; Intracranial Aneurysm - therapy; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Angiography - standards; Male; Medical sciences; Middle Aged; Nervous system; Neurology; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Vascular diseases and vascular malformations of the nervous system
• ISSN: 0039-2499; 1524-4628
• DOI: 10.1161/01.STR.0000209236.06451.3b

To compare the utility of contrast-enhanced MR Angiography (CE-MRA) with digital subtraction angiography (DSA) after endovascular treatment of intracranial aneurysms with Guglielmi detachable coils. From April 1999 to August 2002, 106 patients with 107 aneurysms treated by endovascular coiling using Guglielmi detachable coils underwent simultaneous DSA and CE-MRA at follow-up (mean: 12.9 range: 5 to 27 months). DSA was performed as the standard reference. MR angiographic images were analyzed independently by 2 senior radiologists (J.-Y.G., S.C.) and DSA by a third radiologist (X.L.). Findings were assigned to 1 of 3 categories: complete obliteration (class 1), residual neck (class 2) and residual aneurysm (class 3). DSA at follow-up demonstrated 65 (60.6%) complete obliterations (group 1), 21 (19.7%) residual necks (group 2) and 21 (19.7%) residual aneurysms (group 3). One patient (0.9%) experienced aneurysm rebleed during the follow-up period. Among 101 assessable imaging comparisons, interobserver agreement was determined to be very good for CE-MRA (kappa=0.96) with only 4 discrepancies between both examiners. Comparison between CE-MRA and DSA showed an excellent agreement between techniques (kappa=0.93). Of the 21 with residual necks described on DSA, 20 were seen on CE-MRA. CE-MRA detected all 19 residual aneurysms. CE-MRA after selective embolization of intracranial aneurysm is useful and comparable to DSA in the assessment of aneurysmal recanalization either as residual neck or aneurysmal sac.