Envelope Conformational Changes Induced by Human Immunodeficiency Virus Type 1 Attachment Inhibitors Prevent CD4 Binding and Downstream Entry Events

• Published in: Journal of Virology 2006-04, Vol.80 (8), p.4017-4025
• Main Authors: HO, Hsu-Tso, LI FAN, GONG, Yi-Fei, TAO WANG, ZHIWEI YIN, UEDA, Yasutsugu, MATISKELLA, John, KADOW, John, CLAPHAM, Paul, ROBINSON, James, COLONNO, Richard, LIN, Pin-Fang, NOWICKA-SANS, Beata, MCAULIFFE, Brian, LI, Chang-Ben, YAMANAKA, Gregory, NANNAN ZHOU, HUA FANG, DICKER, Ira, DALTERIO, Richard
• Format: Article
• Language: English
• Subjects: Anti-HIV Agents - pharmacology; Biological and medical sciences; CD4 Antigens - metabolism; Fundamental and applied biological sciences. Psychology; HeLa Cells; HIV Envelope Protein gp120 - chemistry; HIV Envelope Protein gp120 - drug effects; HIV-1 - drug effects; Human immunodeficiency virus 1; Human viral diseases; Humans; Infectious diseases; Medical sciences; Microbiology; Miscellaneous; Piperazines - pharmacology; Protein Conformation; Vaccines and Antiviral Agents; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Virion - drug effects; Virology
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.80.8.4017-4025.2006

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