Analysis of Rab18 and a New Golgin in the Secretory Pathway

: Two new amphibian genes have been isolated and characterized from frog melanotropes, and the level of expression of these genes is related to the secretory status of the cells. Both genes, Rab18 and a novel member of the golgin family of proteins, are ubiquitously expressed in endocrine and nonend...

Full description

Saved in:
Bibliographic Details
Published in:Annals of the New York Academy of Sciences 2005-04, Vol.1040 (1), p.137-139
Main Authors: MALAGÓN, M.M, CRUZ, D, VÁZQUEZ-MARTÍNEZ, R, PEINADO, J R, ANOUAR, Y, TONON, M.C, VAUDRY, H, GRACIA-NAVARRO, F, CASTAÑO, J P
Format: Article
Language:English
Subjects:
Animals
Anura
Autoantigens - analysis
Autoantigens - genetics
Biological Transport - physiology
CHO Cells
Control
Cricetinae
Frogs
Gene expression
Genes
golgin proteins
Pathways
PC12 Cells
Proteins
rab GTP-Binding Proteins - analysis
rab GTP-Binding Proteins - genetics
rab GTP-Binding Proteins - secretion
Rab proteins
Rats
secretory pathway
Signal Transduction - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:: Two new amphibian genes have been isolated and characterized from frog melanotropes, and the level of expression of these genes is related to the secretory status of the cells. Both genes, Rab18 and a novel member of the golgin family of proteins, are ubiquitously expressed in endocrine and nonendocrine tissues, and their corresponding proteins appear to show intracellular distributions associated with discrete vesicular and tubular structures, respectively, suggesting that they may play relevant roles in the regulation of the secretory pathway.
ISSN:0077-8923
1749-6632
DOI:10.1196/annals.1327.017