Anxiety and depression symptoms in psychometrically identified schizotypy

The neurodevelopmental vulnerability for schizophrenia appears to be expressed across a dynamic continuum of adjustment referred to as schizotypy. This model suggests that nonpsychotic schizotypic individuals should exhibit mild and transient forms of symptoms seen in full-blown schizophrenia. Given...

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Bibliographic Details
Published in:Schizophrenia research 2006-04, Vol.83 (2), p.225-235
Main Authors: Lewandowski, Kathryn E., Barrantes-Vidal, Neus, Nelson-Gray, Rosemery O., Clancy, Carolina, Kepley, Hayden O., Kwapil, Thomas R.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Adult and adolescent clinical studies
Anxiety
Anxiety - etiology
Anxiety - psychology
Biological and medical sciences
Depression
Depression - etiology
Depression - psychology
Factor Analysis, Statistical
Female
Humans
Male
Mass Screening - methods
Medical sciences
Mood disorders
Personality disorders
Personality Inventory - statistics & numerical data
Psychology. Psychoanalysis. Psychiatry
Psychometrics
Psychopathology. Psychiatry
Psychoses
Schizophrenia
Schizotypal Personality Disorder - complications
Schizotypy
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Summary:The neurodevelopmental vulnerability for schizophrenia appears to be expressed across a dynamic continuum of adjustment referred to as schizotypy. This model suggests that nonpsychotic schizotypic individuals should exhibit mild and transient forms of symptoms seen in full-blown schizophrenia. Given that depression and anxiety are reported to be comorbid with schizophrenia, the present study examined the relationship of psychometrically defined schizotypy with symptoms of depression and anxiety in a college student sample ( n = 1258). A series of confirmatory factor analyses indicated that a three-factor solution of positive schizotypy, negative schizotypy, and negative affect provided the best solution for self-report measures of schizotypy, anxiety, and depression. As hypothesized, the model indicated that symptoms of depression and anxiety are more strongly associated with the positive-symptom dimension of schizotypy than with the negative-symptom dimension. This is consistent with studies of schizophrenic patients and longitudinal findings that positive-symptom schizotypes are at risk for both mood and non-mood psychotic disorders, while negative-symptom schizotypes appear more specifically at risk for schizophrenia-spectrum disorders.
ISSN:0920-9964
1573-2509
DOI:10.1016/j.schres.2005.11.024