Comparison of Myocardial Perfusion After Successful Primary Percutaneous Coronary Intervention in Patients With ST-Elevation Myocardial Infarction With Versus Without Diabetes Mellitus

Patients with diabetes mellitus (DM) have an adverse prognosis after ST-segment elevation myocardial infarction (STEMI). Whether DM was associated with impaired myocardial reperfusion after successful primary percutaneous coronary intervention for STEMI was investigated. Myocardial reperfusion was a...

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Bibliographic Details
Published in:The American journal of cardiology 2005-06, Vol.95 (11), p.1375-1377
Main Authors: Timmer, Jorik R., van der Horst, Iwan C.C., de Luca, Giuseppe, Ottervanger, Jan Paul, Hoorntje, Jan C.A., de Boer, Menko-Jan, Suryapranata, Harry, Dambrink, Jan-Henk E., Gosselink, Marcel, Zijlstra, Felix, van 't Hof, Arnoud W.J.
Format: Article
Language:English
Subjects:
Angioplasty, Balloon, Coronary
Biological and medical sciences
Cardiology. Vascular system
Clinical trials
Coronary Circulation - physiology
Coronary heart disease
Diabetes
Diabetes Complications - physiopathology
Diabetes Complications - therapy
Diabetes. Impaired glucose tolerance
Electrocardiography
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Heart
Heart attacks
Humans
Male
Medical sciences
Middle Aged
Myocardial Infarction - physiopathology
Myocardial Infarction - therapy
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Summary:Patients with diabetes mellitus (DM) have an adverse prognosis after ST-segment elevation myocardial infarction (STEMI). Whether DM was associated with impaired myocardial reperfusion after successful primary percutaneous coronary intervention for STEMI was investigated. Myocardial reperfusion was assessed by ST-segment resolution and myocardial blush grade (MBG). A total of 386 patients were studied, of whom 64 (17%) had DM. These patients more frequently had reduced MBG (20% vs 10%, p = 0.02) and incomplete ST-segment resolution (55% vs 35%, p = 0.02) compared with patients without DM. After multivariate analysis, DM was still associated with impaired ST resolution (odds ratio 2.1, p = 0.03) and reduced MBG (odds ratio 2.2, p = 0.03).
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2005.01.088